GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
ATPase plasma membrane Ca2+ transporting 3 | ENSG00000067842 | ATP2B3 | chrX:153517676-153582939:+ | 10 | 11.5 |
TNF receptor superfamily member 1B | ENSG00000028137 | TNFRSF1B | chr1:12167003-12209228:+ | 9 | 13 |
ephrin A4 | ENSG00000243364 | EFNA4 | chr1:155063731-155069553:+ | 10 | 13.5 |
CD55 molecule (Cromer blood group) | ENSG00000196352 | CD55 | chr1:207321508-207360966:+ | 9 | 14.5 |
tetraspanin 14 | ENSG00000108219 | TSPAN14 | chr10:80454166-80533123:+ | 10 | 16.5 |
glutamate ionotropic receptor delta type subunit 1 | ENSG00000182771 | GRID1 | chr10:85599555-86366493:- | 10 | 12.5 |
transmembrane 9 superfamily member 3 | ENSG00000077147 | TM9SF3 | chr10:96518109-96587452:- | 9 | 17.5 |
calcium homeostasis modulator 1 | ENSG00000185933 | CALHM1 | chr10:103453387-103458888:- | 10 | 11.5 |
anoctamin 9 | ENSG00000185101 | ANO9 | chr11:417933-442011:- | 9 | 11.5 |
anoctamin 5 | ENSG00000171714 | ANO5 | chr11:22193176-22283357:+ | 9 | 10.5 |
folate receptor beta | ENSG00000165457 | FOLR2 | chr11:72216601-72221950:+ | 10 | 13 |
teneurin transmembrane protein 4 | ENSG00000149256 | TENM4 | chr11:78652831-79440948:- | 10 | 13.5 |
tetraspanin 9 | ENSG00000011105 | TSPAN9 | chr12:3077355-3286564:+ | 10 | 13.5 |
solute carrier family 12 member 6 | ENSG00000140199 | SLC12A6 | chr15:34229996-34338060:- | 9 | 13.5 |
vasorin | ENSG00000168140 | VASN | chr16:4371848-4383528:+ | 9 | 15.5 |
sialophorin | ENSG00000197471 | SPN | chr16:29662979-29670876:+ | 9 | 12.5 |
integrin alpha FG-GAP repeat containing 1 | ENSG00000129636 | ITFG1 | chr16:47154387-47464149:- | 9 | 12.5 |
transmembrane protein 231 | ENSG00000205084 | TMEM231 | chr16:75536744-75556286:- | 10 | 12.5 |
piezo type mechanosensitive ion channel component 1 | ENSG00000103335 | PIEZO1 | chr16:88715343-88785211:- | 10 | 15.5 |
asialoglycoprotein receptor 1 | ENSG00000141505 | ASGR1 | chr17:7173431-7179564:- | 9 | 10.5 |
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