GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
extracellular leucine rich repeat and fibronectin type III domain containing 1ENSG00000225968ELFN1chr7:1688119-1747954:+913
diacylglycerol lipase betaENSG00000164535DAGLBchr7:6409126-6484190:-915.5
glycoprotein nmbENSG00000136235GPNMBchr7:23235967-23275108:+1013.5
NPC1 like intracellular cholesterol transporter 1ENSG00000015520NPC1L1chr7:44512535-44541315:-910.5
ATP binding cassette subfamily B member 4ENSG00000005471ABCB4chr7:87401697-87480435:-910.5
transferrin receptor 2ENSG00000106327TFR2chr7:100620416-100642779:-911.5
acetylcholinesterase (Cartwright blood group)ENSG00000087085ACHEchr7:100889994-100896974:-912.5
mucin 17, cell surface associatedENSG00000169876MUC17chr7:101020072-101058745:+910.5
transient receptor potential cation channel subfamily V member 5ENSG00000127412TRPV5chr7:142908101-142933808:-1011.5
sarcoglycan zetaENSG00000185053SGCZchr8:14089864-15238339:-1011.5
scavenger receptor class A member 5ENSG00000168079SCARA5chr8:27869882-27992727:-910.5
ADAM metallopeptidase domain 9ENSG00000168615ADAM9chr8:38996869-39105144:+916.5
syndecan 2ENSG00000169439SDC2chr8:96493351-96611780:+913.5
programmed cell death 1 ligand 2ENSG00000197646PDCD1LG2chr9:5510570-5571254:+1014.5
crumbs cell polarity complex component 2ENSG00000148204CRB2chr9:123356170-123380324:+1013.5
cytokine receptor like factor 2ENSG00000205755CRLF2chrX:1187549-1212750:-1012.5
gap junction protein beta 1ENSG00000169562GJB1chrX:71215194-71225516:+1011.5
protocadherin 19ENSG00000165194PCDH19chrX:100291644-100410273:-1011.5
glutamate ionotropic receptor AMPA type subunit 3ENSG00000125675GRIA3chrX:123184153-123490915:+1011.5
CD40 ligandENSG00000102245CD40LGchrX:136648193-136660390:+910.5

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