GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
B and T lymphocyte associated | ENSG00000186265 | BTLA | chr3:112463968-112499561:- | 9 | 11.5 |
T cell immunoreceptor with Ig and ITIM domains | ENSG00000181847 | TIGIT | chr3:114276913-114310288:+ | 9 | 10.5 |
solute carrier organic anion transporter family member 2A1 | ENSG00000174640 | SLCO2A1 | chr3:133932696-134052184:- | 10 | 11.5 |
sucrase-isomaltase | ENSG00000090402 | SI | chr3:164978898-165078495:- | 9 | 10.5 |
protocadherin 18 | ENSG00000189184 | PCDH18 | chr4:137518918-137532494:- | 10 | 11.5 |
transmembrane 131 like | ENSG00000121210 | KIAA0922 | chr4:153466346-153636711:+ | 9 | 12.5 |
solute carrier family 9 member A3 | ENSG00000066230 | SLC9A3 | chr5:473310-524332:- | 10 | 11.5 |
solute carrier family 12 member 7 | ENSG00000113504 | SLC12A7 | chr5:1050376-1112035:- | 9 | 14.5 |
cadherin 10 | ENSG00000040731 | CDH10 | chr5:24487100-24644978:- | 10 | 11.5 |
cadherin 9 | ENSG00000113100 | CDH9 | chr5:26880600-27121150:- | 10 | 11.5 |
solute carrier family 23 member 1 | ENSG00000170482 | SLC23A1 | chr5:139367196-139384553:- | 9 | 10.5 |
microfibril associated protein 3 | ENSG00000037749 | MFAP3 | chr5:154038906-154220478:+ | 10 | 12.5 |
solute carrier family 34 member 1 | ENSG00000131183 | SLC34A1 | chr5:177379235-177398848:+ | 10 | 11.5 |
homeostatic iron regulator | ENSG00000010704 | HFE | chr6:26087281-26098343:+ | 10 | 15.5 |
major histocompatibility complex, class I, F | ENSG00000204642 | HLA-F | chr6:29722775-29738528:+ | 10 | 15.5 |
major histocompatibility complex, class II, DR beta 5 | ENSG00000198502 | HLA-DRB5 | chr6:32517343-32530287:- | 9 | 14.5 |
major histocompatibility complex, class II, DP alpha 1 | ENSG00000231389 | HLA-DPA1 | chr6:33064569-33080775:- | 9 | 12.5 |
major histocompatibility complex, class II, DP beta 1 | ENSG00000223865 | HLA-DPB1 | chr6:33075926-33087201:+ | 9 | 13.5 |
gap junction protein alpha 1 | ENSG00000152661 | GJA1 | chr6:121435692-121449727:+ | 10 | 14.5 |
interferon gamma receptor 1 | ENSG00000027697 | IFNGR1 | chr6:137197484-137219449:- | 10 | 14.5 |
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