GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
Fc fragment of IgG receptor Ia | ENSG00000150337 | FCGR1A | chr1:149782671-149792518:+ | 9 | 12.5 |
Fc receptor like 5 | ENSG00000143297 | FCRL5 | chr1:157513377-157552520:- | 9 | 11.5 |
Fc receptor like 3 | ENSG00000160856 | FCRL3 | chr1:157674321-157700857:- | 9 | 11.5 |
Fc receptor like 2 | ENSG00000132704 | FCRL2 | chr1:157745733-157777132:- | 9 | 11.5 |
CD84 molecule | ENSG00000066294 | CD84 | chr1:160541095-160579516:- | 9 | 14.5 |
signaling lymphocytic activation molecule family member 1 | ENSG00000117090 | SLAMF1 | chr1:160608100-160647295:- | 9 | 12.5 |
Fc fragment of IgG receptor IIIb | ENSG00000162747 | FCGR3B | chr1:161623196-161631963:- | 9 | 11.5 |
solute carrier family 19 member 2 | ENSG00000117479 | SLC19A2 | chr1:169463909-169486003:- | 10 | 13.5 |
TNF superfamily member 18 | ENSG00000120337 | TNFSF18 | chr1:173039960-173050963:- | 9 | 10.5 |
plexin A2 | ENSG00000076356 | PLXNA2 | chr1:208022242-208244320:- | 10 | 14.5 |
zona pellucida glycoprotein 4 | ENSG00000116996 | ZP4 | chr1:237877864-237890922:- | 9 | 10.5 |
V-set and transmembrane domain containing 4 | ENSG00000165633 | VSTM4 | chr10:49014245-49115509:- | 9 | 10.5 |
V-set immunoregulatory receptor | ENSG00000107738 | C10orf54 | chr10:71747559-71773498:- | 9 | 13.5 |
potassium two pore domain channel subfamily K member 18 | ENSG00000186795 | KCNK18 | chr10:117197489-117210299:+ | 10 | 11.5 |
solute carrier family 22 member 6 | ENSG00000197901 | SLC22A6 | chr11:62936385-62984983:- | 9 | 10.5 |
fibronectin leucine rich transmembrane protein 1 | ENSG00000126500 | FLRT1 | chr11:64103188-64119173:+ | 9 | 11.5 |
solute carrier family 22 member 11 | ENSG00000168065 | SLC22A11 | chr11:64555626-64572875:+ | 9 | 11.5 |
beta-secretase 1 | ENSG00000186318 | BACE1 | chr11:117285207-117316259:- | 9 | 10.5 |
CXADR like membrane protein | ENSG00000166250 | CLMP | chr11:123069865-123195281:- | 9 | 12.5 |
TNF receptor superfamily member 1A | ENSG00000067182 | TNFRSF1A | chr12:6328757-6342114:- | 9 | 12.5 |
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