GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
protein tyrosine phosphatase receptor type R | ENSG00000153233 | PTPRR | chr12:70638073-70920843:- | 9 | 10.5 |
G protein-coupled receptor 65 | ENSG00000140030 | GPR65 | chr14:88005124-88014811:+ | 10 | 13 |
G protein-coupled receptor 132 | ENSG00000183484 | GPR132 | chr14:105049389-105065445:- | 9 | 12 |
cadherin 8 | ENSG00000150394 | CDH8 | chr16:61647242-62037035:- | 10 | 12.5 |
desmocollin 3 | ENSG00000134762 | DSC3 | chr18:30990008-31042815:- | 10 | 13.5 |
solute carrier family 14 member 1 (Kidd blood group) | ENSG00000141469 | SLC14A1 | chr18:45724127-45752520:+ | 9 | 12.5 |
myelin associated glycoprotein | ENSG00000105695 | MAG | chr19:35292125-35313804:+ | 9 | 10.5 |
transient receptor potential cation channel subfamily M member 4 | ENSG00000130529 | TRPM4 | chr19:49157741-49211836:+ | 9 | 13.5 |
interleukin 1 receptor like 1 | ENSG00000115602 | IL1RL1 | chr2:102311502-102352037:+ | 9 | 10.5 |
glycophorin C (Gerbich blood group) | ENSG00000136732 | GYPC | chr2:126655933-126696675:+ | 10 | 14.5 |
cadherin 26 | ENSG00000124215 | CDH26 | chr20:59958427-60034011:+ | 10 | 11.5 |
cadherin EGF LAG seven-pass G-type receptor 3 | ENSG00000008300 | CELSR3 | chr3:48636469-48662915:- | 9 | 12 |
cell adhesion molecule 2 | ENSG00000175161 | CADM2 | chr3:84958981-86074429:+ | 9 | 11 |
immunoglobulin like domain containing receptor 1 | ENSG00000145103 | ILDR1 | chr3:121987323-122022204:- | 9 | 10.5 |
succinate receptor 1 | ENSG00000198829 | SUCNR1 | chr3:151873643-151884619:+ | 9 | 11 |
corin, serine peptidase | ENSG00000145244 | CORIN | chr4:47593998-47838106:- | 9 | 10.5 |
microfibril associated protein 3 like | ENSG00000198948 | MFAP3L | chr4:169986597-170033031:- | 10 | 12.5 |
solute carrier family 1 member 3 | ENSG00000079215 | SLC1A3 | chr5:36606355-36688334:+ | 9 | 17.5 |
heparin binding EGF like growth factor | ENSG00000113070 | HBEGF | chr5:140332843-140346631:- | 9 | 10.5 |
butyrophilin subfamily 3 member A1 | ENSG00000026950 | BTN3A1 | chr6:26402237-26415216:+ | 10 | 15.5 |
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