GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
protein tyrosine phosphatase receptor type RENSG00000153233PTPRRchr12:70638073-70920843:-910.5
G protein-coupled receptor 65ENSG00000140030GPR65chr14:88005124-88014811:+1013
G protein-coupled receptor 132ENSG00000183484GPR132chr14:105049389-105065445:-912
cadherin 8ENSG00000150394CDH8chr16:61647242-62037035:-1012.5
desmocollin 3ENSG00000134762DSC3chr18:30990008-31042815:-1013.5
solute carrier family 14 member 1 (Kidd blood group)ENSG00000141469SLC14A1chr18:45724127-45752520:+912.5
myelin associated glycoproteinENSG00000105695MAGchr19:35292125-35313804:+910.5
transient receptor potential cation channel subfamily M member 4ENSG00000130529TRPM4chr19:49157741-49211836:+913.5
interleukin 1 receptor like 1ENSG00000115602IL1RL1chr2:102311502-102352037:+910.5
glycophorin C (Gerbich blood group)ENSG00000136732GYPCchr2:126655933-126696675:+1014.5
cadherin 26ENSG00000124215CDH26chr20:59958427-60034011:+1011.5
cadherin EGF LAG seven-pass G-type receptor 3ENSG00000008300CELSR3chr3:48636469-48662915:-912
cell adhesion molecule 2ENSG00000175161CADM2chr3:84958981-86074429:+911
immunoglobulin like domain containing receptor 1ENSG00000145103ILDR1chr3:121987323-122022204:-910.5
succinate receptor 1ENSG00000198829SUCNR1chr3:151873643-151884619:+911
corin, serine peptidaseENSG00000145244CORINchr4:47593998-47838106:-910.5
microfibril associated protein 3 likeENSG00000198948MFAP3Lchr4:169986597-170033031:-1012.5
solute carrier family 1 member 3ENSG00000079215SLC1A3chr5:36606355-36688334:+917.5
heparin binding EGF like growth factorENSG00000113070HBEGFchr5:140332843-140346631:-910.5
butyrophilin subfamily 3 member A1ENSG00000026950BTN3A1chr6:26402237-26415216:+1015.5

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