GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
G protein-coupled receptor 63 | ENSG00000112218 | GPR63 | chr6:96794126-96837463:- | 9 | 11 |
neuromedin B receptor | ENSG00000135577 | NMBR | chr6:142058330-142088799:- | 10 | 12 |
frizzled class receptor 6 | ENSG00000164930 | FZD6 | chr8:103298433-103332866:+ | 10 | 15 |
thyrotropin releasing hormone receptor | ENSG00000174417 | TRHR | chr8:109086621-109119584:+ | 9 | 11 |
patched 1 | ENSG00000185920 | PTCH1 | chr9:95442980-95517057:- | 10 | 14.5 |
ATP binding cassette subfamily A member 1 | ENSG00000165029 | ABCA1 | chr9:104781002-104928237:- | 9 | 19.5 |
cysteinyl leukotriene receptor 1 | ENSG00000173198 | CYSLTR1 | chrX:78271464-78327691:- | 10 | 14 |
P2Y receptor family member 10 | ENSG00000078589 | P2RY10 | chrX:78945332-78961954:+ | 10 | 14 |
G protein-coupled receptor 174 | ENSG00000147138 | GPR174 | chrX:79170972-79172229:+ | 10 | 12 |
G protein-coupled receptor 50 | ENSG00000102195 | GPR50 | chrX:151176653-151181465:+ | 10 | 13 |
cadherin EGF LAG seven-pass G-type receptor 2 | ENSG00000143126 | CELSR2 | chr1:109250019-109275750:+ | 9 | 15 |
V-set domain containing T cell activation inhibitor 1 | ENSG00000134258 | VTCN1 | chr1:117143587-117210960:- | 10 | 11.5 |
interleukin 6 receptor | ENSG00000160712 | IL6R | chr1:154405193-154469450:+ | 10 | 12.5 |
CD1a molecule | ENSG00000158477 | CD1A | chr1:158254137-158258269:+ | 10 | 11.5 |
Fc fragment of IgE receptor Ia | ENSG00000179639 | FCER1A | chr1:159289714-159308224:+ | 9 | 10.5 |
polymeric immunoglobulin receptor | ENSG00000162896 | PIGR | chr1:206928518-206946466:- | 9 | 10.5 |
complement C3b/C4b receptor 1 (Knops blood group) | ENSG00000203710 | CR1 | chr1:207496147-207640647:+ | 9 | 12 |
protocadherin related 15 | ENSG00000150275 | PCDH15 | chr10:53802771-55627942:- | 10 | 13 |
cadherin related family member 5 | ENSG00000099834 | CDHR5 | chr11:616565-626078:- | 10 | 11.5 |
killer cell lectin like receptor K1 | ENSG00000213809 | KLRK1 | chr12:10372353-10391874:- | 10 | 12.5 |
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