GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
G protein-coupled receptor 63ENSG00000112218GPR63chr6:96794126-96837463:-911
neuromedin B receptorENSG00000135577NMBRchr6:142058330-142088799:-1012
frizzled class receptor 6ENSG00000164930FZD6chr8:103298433-103332866:+1015
thyrotropin releasing hormone receptorENSG00000174417TRHRchr8:109086621-109119584:+911
patched 1ENSG00000185920PTCH1chr9:95442980-95517057:-1014.5
ATP binding cassette subfamily A member 1ENSG00000165029ABCA1chr9:104781002-104928237:-919.5
cysteinyl leukotriene receptor 1ENSG00000173198CYSLTR1chrX:78271464-78327691:-1014
P2Y receptor family member 10ENSG00000078589P2RY10chrX:78945332-78961954:+1014
G protein-coupled receptor 174ENSG00000147138GPR174chrX:79170972-79172229:+1012
G protein-coupled receptor 50ENSG00000102195GPR50chrX:151176653-151181465:+1013
cadherin EGF LAG seven-pass G-type receptor 2ENSG00000143126CELSR2chr1:109250019-109275750:+915
V-set domain containing T cell activation inhibitor 1ENSG00000134258VTCN1chr1:117143587-117210960:-1011.5
interleukin 6 receptorENSG00000160712IL6Rchr1:154405193-154469450:+1012.5
CD1a moleculeENSG00000158477CD1Achr1:158254137-158258269:+1011.5
Fc fragment of IgE receptor IaENSG00000179639FCER1Achr1:159289714-159308224:+910.5
polymeric immunoglobulin receptorENSG00000162896PIGRchr1:206928518-206946466:-910.5
complement C3b/C4b receptor 1 (Knops blood group)ENSG00000203710CR1chr1:207496147-207640647:+912
protocadherin related 15ENSG00000150275PCDH15chr10:53802771-55627942:-1013
cadherin related family member 5ENSG00000099834CDHR5chr11:616565-626078:-1011.5
killer cell lectin like receptor K1ENSG00000213809KLRK1chr12:10372353-10391874:-1012.5

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