GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
prostaglandin E receptor 2 | ENSG00000125384 | PTGER2 | chr14:52314305-52328606:+ | 9 | 12 |
gamma-aminobutyric acid type A receptor subunit beta3 | ENSG00000166206 | GABRB3 | chr15:26543546-26939539:- | 10 | 13.5 |
gamma-aminobutyric acid type A receptor subunit alpha5 | ENSG00000186297 | GABRA5 | chr15:26866363-26949207:+ | 10 | 13.5 |
somatostatin receptor 5 | ENSG00000162009 | SSTR5 | chr16:1078781-1080142:+ | 10 | 12 |
glucagon like peptide 2 receptor | ENSG00000065325 | GLP2R | chr17:9822206-9892102:+ | 9 | 11 |
G protein-coupled receptor 142 | ENSG00000257008 | GPR142 | chr17:74367407-74372622:+ | 9 | 11 |
sphingosine-1-phosphate receptor 4 | ENSG00000125910 | S1PR4 | chr19:3172346-3180332:+ | 9 | 13 |
sphingosine-1-phosphate receptor 5 | ENSG00000180739 | S1PR5 | chr19:10512742-10517931:- | 9 | 12 |
prostaglandin I2 receptor | ENSG00000160013 | PTGIR | chr19:46620468-46625118:- | 9 | 11 |
CD8b molecule | ENSG00000172116 | CD8B | chr2:86815339-86861924:- | 9 | 11 |
G protein-coupled receptor 39 | ENSG00000183840 | GPR39 | chr2:132416574-132646559:+ | 9 | 11 |
frizzled class receptor 7 | ENSG00000155760 | FZD7 | chr2:202034587-202038445:+ | 10 | 15 |
G protein-coupled receptor 156 | ENSG00000175697 | GPR156 | chr3:120164645-120285094:- | 10 | 12 |
adrenoceptor alpha 2C | ENSG00000184160 | ADRA2C | chr4:3766348-3768526:+ | 10 | 12 |
neuropeptide FF receptor 2 | ENSG00000056291 | NPFFR2 | chr4:72031804-72148067:+ | 10 | 12 |
growth hormone receptor | ENSG00000112964 | GHR | chr5:42423777-42721878:+ | 10 | 12.5 |
5-hydroxytryptamine receptor 1A | ENSG00000178394 | HTR1A | chr5:63960356-63962507:- | 10 | 12 |
adrenoceptor alpha 1B | ENSG00000170214 | ADRA1B | chr5:159916783-159972544:+ | 10 | 12 |
MAS1 proto-oncogene like, G protein-coupled receptor | ENSG00000204687 | MAS1L | chr6:29486697-29487956:- | 9 | 11 |
gamma-aminobutyric acid type B receptor subunit 1 | ENSG00000204681 | GABBR1 | chr6:29555629-29633976:- | 10 | 12 |
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