GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
prostaglandin D2 receptor 2 | ENSG00000183134 | PTGDR2 | chr11:60850940-60855971:- | 10 | 14 |
ATPase plasma membrane Ca2+ transporting 1 | ENSG00000070961 | ATP2B1 | chr12:89588049-89709300:- | 10 | 21 |
presenilin 1 | ENSG00000080815 | PSEN1 | chr14:73136418-73223691:+ | 10 | 17.5 |
solute carrier family 4 member 1 (Diego blood group) | ENSG00000004939 | SLC4A1 | chr17:44248385-44268141:- | 9 | 14.5 |
sphingosine-1-phosphate receptor 2 | ENSG00000267534 | S1PR2 | chr19:10221435-10231272:- | 9 | 14 |
gastric inhibitory polypeptide receptor | ENSG00000010310 | GIPR | chr19:45668244-45683724:+ | 9 | 12 |
follicle stimulating hormone receptor | ENSG00000170820 | FSHR | chr2:48962157-49154537:- | 10 | 12.5 |
gamma-aminobutyric acid type B receptor subunit 2 | ENSG00000136928 | GABBR2 | chr9:98288109-98709197:- | 10 | 13 |
5-hydroxytryptamine receptor 1D | ENSG00000179546 | HTR1D | chr1:23191895-23194729:- | 10 | 12 |
mucin 1, cell surface associated | ENSG00000185499 | MUC1 | chr1:155185824-155192916:- | 9 | 13 |
G protein-coupled receptor 37 like 1 | ENSG00000170075 | GPR37L1 | chr1:202122858-202133592:+ | 9 | 11 |
olfactory receptor family 2 subfamily C member 3 | ENSG00000196242 | OR2C3 | chr1:247530132-247533839:- | 9 | 11 |
tachykinin receptor 2 | ENSG00000075073 | TACR2 | chr10:69403903-69416867:- | 10 | 12 |
CD81 molecule | ENSG00000110651 | CD81 | chr11:2376177-2397419:+ | 10 | 21.5 |
aquaporin 5 | ENSG00000161798 | AQP5 | chr12:49961870-49965681:+ | 10 | 14.5 |
leucine rich repeat containing G protein-coupled receptor 5 | ENSG00000139292 | LGR5 | chr12:71439770-71586310:+ | 10 | 13 |
hydroxycarboxylic acid receptor 2 | ENSG00000182782 | HCAR2 | chr12:122701293-122703343:- | 9 | 11 |
lysophosphatidic acid receptor 6 | ENSG00000139679 | LPAR6 | chr13:48389567-48444704:- | 10 | 13 |
oxoglutarate receptor 1 | ENSG00000165621 | OXGR1 | chr13:96985719-96994730:- | 9 | 11 |
leukotriene B4 receptor 2 | ENSG00000213906 | LTB4R2 | chr14:24305734-24312053:+ | 10 | 12 |
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