GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
natriuretic peptide receptor 2ENSG00000159899NPR2chr9:35792154-35809732:+1012
reversion inducing cysteine rich protein with kazal motifsENSG00000122707RECKchr9:36036433-36124451:+1115.5
interleukin 13 receptor subunit alpha 2ENSG00000123496IL13RA2chrX:115003975-115019977:-1113.5
SLIT and NTRK like family member 4ENSG00000179542SLITRK4chrX:143622790-143635777:-1113.5
natriuretic peptide receptor 1ENSG00000169418NPR1chr1:153678637-153693992:+1013
GDNF family receptor alpha 1ENSG00000151892GFRA1chr10:116056925-116273467:-1113
CD59 molecule (CD59 blood group)ENSG00000085063CD59chr11:33698261-33736445:-1118.5
CD82 moleculeENSG00000085117CD82chr11:44564427-44620363:+1115.5
suppression of tumorigenicity 14ENSG00000149418ST14chr11:130159562-130210376:+1015.5
neurotriminENSG00000182667NTMchr11:131370478-132336822:+1014
protein tyrosine phosphatase receptor type BENSG00000127329PTPRBchr12:70515866-70637440:-1013
mesothelinENSG00000102854MSLNchr16:643262-768865:+1013
ATP binding cassette subfamily C member 6ENSG00000091262ABCC6chr16:16148928-16223522:-1011.5
carboxypeptidase DENSG00000108582CPDchr17:30378905-30469989:+1015
reticulon 4ENSG00000115310RTN4chr2:54972187-55112621:-1018.5
solute carrier family 1 member 4ENSG00000115902SLC1A4chr2:64988477-65023865:+1017.5
solute carrier family 9 member A4ENSG00000180251SLC9A4chr2:102473303-102533972:+1112.5
solute carrier family 5 member 3ENSG00000198743SLC5A3chr21:34073570-34106260:+1114.5
solute carrier family 5 member 1ENSG00000100170SLC5A1chr22:32043032-32113029:+1112.5
solute carrier family 12 member 2ENSG00000064651SLC12A2chr5:128083766-128189688:+1117.5

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