GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
natriuretic peptide receptor 2 | ENSG00000159899 | NPR2 | chr9:35792154-35809732:+ | 10 | 12 |
reversion inducing cysteine rich protein with kazal motifs | ENSG00000122707 | RECK | chr9:36036433-36124451:+ | 11 | 15.5 |
interleukin 13 receptor subunit alpha 2 | ENSG00000123496 | IL13RA2 | chrX:115003975-115019977:- | 11 | 13.5 |
SLIT and NTRK like family member 4 | ENSG00000179542 | SLITRK4 | chrX:143622790-143635777:- | 11 | 13.5 |
natriuretic peptide receptor 1 | ENSG00000169418 | NPR1 | chr1:153678637-153693992:+ | 10 | 13 |
GDNF family receptor alpha 1 | ENSG00000151892 | GFRA1 | chr10:116056925-116273467:- | 11 | 13 |
CD59 molecule (CD59 blood group) | ENSG00000085063 | CD59 | chr11:33698261-33736445:- | 11 | 18.5 |
CD82 molecule | ENSG00000085117 | CD82 | chr11:44564427-44620363:+ | 11 | 15.5 |
suppression of tumorigenicity 14 | ENSG00000149418 | ST14 | chr11:130159562-130210376:+ | 10 | 15.5 |
neurotrimin | ENSG00000182667 | NTM | chr11:131370478-132336822:+ | 10 | 14 |
protein tyrosine phosphatase receptor type B | ENSG00000127329 | PTPRB | chr12:70515866-70637440:- | 10 | 13 |
mesothelin | ENSG00000102854 | MSLN | chr16:643262-768865:+ | 10 | 13 |
ATP binding cassette subfamily C member 6 | ENSG00000091262 | ABCC6 | chr16:16148928-16223522:- | 10 | 11.5 |
carboxypeptidase D | ENSG00000108582 | CPD | chr17:30378905-30469989:+ | 10 | 15 |
reticulon 4 | ENSG00000115310 | RTN4 | chr2:54972187-55112621:- | 10 | 18.5 |
solute carrier family 1 member 4 | ENSG00000115902 | SLC1A4 | chr2:64988477-65023865:+ | 10 | 17.5 |
solute carrier family 9 member A4 | ENSG00000180251 | SLC9A4 | chr2:102473303-102533972:+ | 11 | 12.5 |
solute carrier family 5 member 3 | ENSG00000198743 | SLC5A3 | chr21:34073570-34106260:+ | 11 | 14.5 |
solute carrier family 5 member 1 | ENSG00000100170 | SLC5A1 | chr22:32043032-32113029:+ | 11 | 12.5 |
solute carrier family 12 member 2 | ENSG00000064651 | SLC12A2 | chr5:128083766-128189688:+ | 11 | 17.5 |
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