GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
ssemaphorin 4F | ENSG00000135622 | SEMA4F | chr2:74654228-74683853:+ | 11 | 13.5 |
signal regulatory protein alpha | ENSG00000198053 | SIRPA | chr20:1894167-1940592:+ | 11 | 17.5 |
thrombomodulin | ENSG00000178726 | THBD | chr20:23045633-23049741:- | 10 | 13.5 |
syndecan 4 | ENSG00000124145 | SDC4 | chr20:45325288-45348424:- | 10 | 15.5 |
macrophage stimulating 1 receptor | ENSG00000164078 | MST1R | chr3:49887002-49903873:- | 11 | 14.5 |
protein tyrosine phosphatase receptor type G | ENSG00000144724 | PTPRG | chr3:61561569-62297613:+ | 10 | 17.5 |
CD96 molecule | ENSG00000153283 | CD96 | chr3:111292719-111665750:+ | 10 | 13.5 |
CD80 molecule | ENSG00000121594 | CD80 | chr3:119524293-119559602:- | 11 | 13.5 |
podocalyxin like 2 | ENSG00000114631 | PODXL2 | chr3:127629181-127672809:+ | 10 | 14.5 |
glycoprotein V platelet | ENSG00000178732 | GP5 | chr3:194394821-194398354:- | 10 | 13.5 |
prominin 1 | ENSG00000007062 | PROM1 | chr4:15963076-16084378:- | 11 | 14.5 |
natriuretic peptide receptor 3 | ENSG00000113389 | NPR3 | chr5:32689070-32791724:+ | 10 | 13.5 |
teneurin transmembrane protein 2 | ENSG00000145934 | TENM2 | chr5:167284799-168264157:+ | 11 | 15.5 |
CD83 molecule | ENSG00000112149 | CD83 | chr6:14117256-14136918:+ | 10 | 12.5 |
protein tyrosine kinase 7 (inactive) | ENSG00000112655 | PTK7 | chr6:43076268-43161719:+ | 10 | 17.5 |
ectonucleotide pyrophosphatase/phosphodiesterase 4 | ENSG00000001561 | ENPP4 | chr6:46129993-46146699:+ | 10 | 13.5 |
vanin 2 | ENSG00000112303 | VNN2 | chr6:132743870-132763459:- | 10 | 13.5 |
solute carrier family 29 member 4 | ENSG00000164638 | SLC29A4 | chr7:5274369-5306870:+ | 11 | 12.5 |
claudin 12 | ENSG00000157224 | CLDN12 | chr7:90383721-90513402:+ | 10 | 11.5 |
macrophage scavenger receptor 1 | ENSG00000038945 | MSR1 | chr8:16107878-16567490:- | 11 | 14.5 |
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