GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
interleukin 17 receptor B | ENSG00000056736 | IL17RB | chr3:53846580-53865800:+ | 10 | 12.5 |
EPH receptor A3 | ENSG00000044524 | EPHA3 | chr3:89107524-89482134:+ | 11 | 13.5 |
CD200 molecule | ENSG00000091972 | CD200 | chr3:112332347-112362812:+ | 10 | 15.5 |
EPH receptor B3 | ENSG00000182580 | EPHB3 | chr3:184561784-184582409:+ | 11 | 17.5 |
EPH receptor A5 | ENSG00000145242 | EPHA5 | chr4:65319563-65670495:- | 11 | 15.5 |
embigin | ENSG00000170571 | EMB | chr5:50396192-50443248:- | 11 | 16.5 |
protocadherin alpha 11 | ENSG00000249158 | PCDHA11 | chr5:140868183-141012344:+ | 11 | 12.5 |
sarcoglycan delta | ENSG00000170624 | SGCD | chr5:155870344-156767788:+ | 11 | 13.5 |
fibroblast growth factor receptor 4 | ENSG00000160867 | FGFR4 | chr5:177086886-177098144:+ | 11 | 12.5 |
megakaryocyte and platelet inhibitory receptor G6b | ENSG00000204420 | C6orf25 | chr6:31718594-31726714:+ | 11 | 12.5 |
CD164 molecule | ENSG00000135535 | CD164 | chr6:109366514-109382559:- | 10 | 11.5 |
thrombospondin type 1 domain containing 7A | ENSG00000005108 | THSD7A | chr7:11370357-11832198:- | 11 | 13.5 |
receptor activity modifying protein 3 | ENSG00000122679 | RAMP3 | chr7:45157791-45186302:+ | 11 | 12.5 |
EPH receptor B4 | ENSG00000196411 | EPHB4 | chr7:100802565-100827521:- | 11 | 16.5 |
transmembrane protein with EGF like and two follistatin like domains 1 | ENSG00000241697 | TMEFF1 | chr9:100473113-100577636:+ | 10 | 12.5 |
quiescin sulfhydryl oxidase 2 | ENSG00000165661 | QSOX2 | chr9:136206333-136245841:- | 11 | 15.5 |
sodium channel epithelial 1 subunit delta | ENSG00000162572 | SCNN1D | chr1:1280436-1292029:+ | 10 | 11.5 |
TNF receptor superfamily member 9 | ENSG00000049249 | TNFRSF9 | chr1:7915894-7943165:- | 10 | 12.5 |
solute carrier family 2 member 5 | ENSG00000142583 | SLC2A5 | chr1:9035107-9088478:- | 10 | 15.5 |
glutamate ionotropic receptor kainate type subunit 3 | ENSG00000163873 | GRIK3 | chr1:36795527-37034129:- | 11 | 12.5 |
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