GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
interleukin 4 receptorENSG00000077238IL4Rchr16:27313668-27364778:+1014.5
cadherin 11ENSG00000140937CDH11chr16:64943753-65126112:-1114.5
cadherin 15ENSG00000129910CDH15chr16:89171767-89195492:+1112.5
cystinosin, lysosomal cystine transporterENSG00000040531CTNSchr17:3636468-3661542:+1013
neuroligin 2ENSG00000169992NLGN2chr17:7404874-7419860:+1114.5
mast cell immunoglobulin like receptor 1ENSG00000271605MILR1chr17:64449037-64468643:+1014.5
cadherin 19ENSG00000071991CDH19chr18:66501083-66604138:-1113.5
semaphorin 6BENSG00000167680SEMA6Bchr19:4542593-4559808:-1112.5
plasmalemma vesicle associated proteinENSG00000130300PLVAPchr19:17351448-17377350:-1012.5
CD22 moleculeENSG00000012124CD22chr19:35319261-35347355:+1013.5
CD79a moleculeENSG00000105369CD79Achr19:41877120-41881372:+1114.5
sialic acid binding Ig like lectin 6ENSG00000105492SIGLEC6chr19:51519525-51531856:-1011.5
leukocyte immunoglobulin like receptor B1ENSG00000104972LILRB1chr19:54617158-54700954:+1014.5
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3ENSG00000243772KIR2DL3chr19:54724459-54767884:+1012.5
phospholipase A2 receptor 1ENSG00000153246PLA2R1chr2:159932006-160062610:-1011.5
sialic acid binding Ig like lectin 1ENSG00000088827SIGLEC1chr20:3686970-3707128:-1013.5
prion proteinENSG00000171867PRNPchr20:4686236-4701590:+1120.5
protein C receptorENSG00000101000PROCRchr20:35172073-35177362:+1018.5
CD40 moleculeENSG00000101017CD40chr20:46118272-46129863:+1015.5
gamma-glutamyltransferase 1ENSG00000100031GGT1chr22:24583750-24629005:+1116.5

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