GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
interleukin 4 receptor | ENSG00000077238 | IL4R | chr16:27313668-27364778:+ | 10 | 14.5 |
cadherin 11 | ENSG00000140937 | CDH11 | chr16:64943753-65126112:- | 11 | 14.5 |
cadherin 15 | ENSG00000129910 | CDH15 | chr16:89171767-89195492:+ | 11 | 12.5 |
cystinosin, lysosomal cystine transporter | ENSG00000040531 | CTNS | chr17:3636468-3661542:+ | 10 | 13 |
neuroligin 2 | ENSG00000169992 | NLGN2 | chr17:7404874-7419860:+ | 11 | 14.5 |
mast cell immunoglobulin like receptor 1 | ENSG00000271605 | MILR1 | chr17:64449037-64468643:+ | 10 | 14.5 |
cadherin 19 | ENSG00000071991 | CDH19 | chr18:66501083-66604138:- | 11 | 13.5 |
semaphorin 6B | ENSG00000167680 | SEMA6B | chr19:4542593-4559808:- | 11 | 12.5 |
plasmalemma vesicle associated protein | ENSG00000130300 | PLVAP | chr19:17351448-17377350:- | 10 | 12.5 |
CD22 molecule | ENSG00000012124 | CD22 | chr19:35319261-35347355:+ | 10 | 13.5 |
CD79a molecule | ENSG00000105369 | CD79A | chr19:41877120-41881372:+ | 11 | 14.5 |
sialic acid binding Ig like lectin 6 | ENSG00000105492 | SIGLEC6 | chr19:51519525-51531856:- | 10 | 11.5 |
leukocyte immunoglobulin like receptor B1 | ENSG00000104972 | LILRB1 | chr19:54617158-54700954:+ | 10 | 14.5 |
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3 | ENSG00000243772 | KIR2DL3 | chr19:54724459-54767884:+ | 10 | 12.5 |
phospholipase A2 receptor 1 | ENSG00000153246 | PLA2R1 | chr2:159932006-160062610:- | 10 | 11.5 |
sialic acid binding Ig like lectin 1 | ENSG00000088827 | SIGLEC1 | chr20:3686970-3707128:- | 10 | 13.5 |
prion protein | ENSG00000171867 | PRNP | chr20:4686236-4701590:+ | 11 | 20.5 |
protein C receptor | ENSG00000101000 | PROCR | chr20:35172073-35177362:+ | 10 | 18.5 |
CD40 molecule | ENSG00000101017 | CD40 | chr20:46118272-46129863:+ | 10 | 15.5 |
gamma-glutamyltransferase 1 | ENSG00000100031 | GGT1 | chr22:24583750-24629005:+ | 11 | 16.5 |
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