GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
CD2 moleculeENSG00000116824CD2chr1:116754385-116769228:+1013.5
Fc receptor like 6ENSG00000181036FCRL6chr1:159800511-159816251:+1011.5
myelin protein zeroENSG00000158887MPZchr1:161304735-161309972:-1011.5
Fc fragment of IgG receptor IIbENSG00000072694FCGR2Bchr1:161581311-161678654:+1014.5
CD46 moleculeENSG00000117335CD46chr1:207752057-207795513:+1018
integrin subunit alpha 8ENSG00000077943ITGA8chr10:15513949-15720125:-1013.5
natural killer cell cytotoxicity receptor 3 ligand 1ENSG00000188211NCR3LG1chr11:17351726-17377341:+1012.5
CD6 moleculeENSG00000013725CD6chr11:60971680-61020377:+1114.5
CD5 moleculeENSG00000110448CD5chr11:61102395-61127852:+1112.5
transmembrane serine protease 5ENSG00000166682TMPRSS5chr11:113687550-113706373:-1011.5
interleukin 10 receptor subunit alphaENSG00000110324IL10RAchr11:117986348-118001483:+1113.5
sodium voltage-gated channel beta subunit 4ENSG00000177098SCN4Bchr11:118133377-118152888:-1011.5
junction adhesion molecule likeENSG00000160593AMICA1chr11:118193740-118225094:-1012.5
CD3d moleculeENSG00000167286CD3Dchr11:118338954-118342744:-1113.5
CD3g moleculeENSG00000160654CD3Gchr11:118344344-118355161:+1112.5
lysosomal associated membrane protein 1ENSG00000185896LAMP1chr13:113297241-113323672:+1018.5
proline rich membrane anchor 1ENSG00000175785PRIMA1chr14:93718298-93788481:-1011.5
TYRO3 protein tyrosine kinaseENSG00000092445TYRO3chr15:41557675-41583586:+1112.5
leucine rich repeat and Ig domain containing 1ENSG00000169783LINGO1chr15:77613027-77820900:-1011.5
TNF receptor superfamily member 17ENSG00000048462TNFRSF17chr16:11965107-11968068:+1113.5

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