GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
leukotriene B4 receptor | ENSG00000213903 | LTB4R | chr14:24311450-24318036:+ | 11 | 14 |
CD19 molecule | ENSG00000177455 | CD19 | chr16:28931939-28939346:+ | 11 | 15 |
C-X3-C motif chemokine ligand 1 | ENSG00000006210 | CX3CL1 | chr16:57372458-57385048:+ | 10 | 13.5 |
C-C motif chemokine receptor 7 | ENSG00000126353 | CCR7 | chr17:40553769-40565472:- | 11 | 14 |
frizzled class receptor 2 | ENSG00000180340 | FZD2 | chr17:44557459-44559570:+ | 11 | 16 |
adhesion G protein-coupled receptor E2 | ENSG00000127507 | ADGRE2 | chr19:14732393-14778541:- | 11 | 17 |
F2R like thrombin or trypsin receptor 3 | ENSG00000127533 | F2RL3 | chr19:16888860-16892606:+ | 11 | 14 |
neuromedin U receptor 1 | ENSG00000171596 | NMUR1 | chr2:231523160-231530495:- | 10 | 12 |
neurotensin receptor 1 | ENSG00000101188 | NTSR1 | chr20:62708837-62762771:+ | 10 | 12 |
C-C motif chemokine receptor 4 | ENSG00000183813 | CCR4 | chr3:32951574-32956349:+ | 11 | 14 |
vasoactive intestinal peptide receptor 1 | ENSG00000114812 | VIPR1 | chr3:42489299-42537573:+ | 10 | 13 |
CD86 molecule | ENSG00000114013 | CD86 | chr3:122055366-122121139:+ | 11 | 15.5 |
fibroblast growth factor receptor 3 | ENSG00000068078 | FGFR3 | chr4:1793307-1808872:+ | 11 | 13.5 |
endothelin receptor type A | ENSG00000151617 | EDNRA | chr4:147480917-147544954:+ | 10 | 12 |
major histocompatibility complex, class II, DR beta 1 | ENSG00000196126 | HLA-DRB1 | chr6:32552990-32589848:- | 10 | 16 |
major histocompatibility complex, class II, DQ alpha 1 | ENSG00000196735 | HLA-DQA1 | chr6:32628179-32647062:+ | 10 | 15 |
EPH receptor A1 | ENSG00000146904 | EPHA1 | chr7:143390289-143408892:- | 11 | 13.5 |
sphingosine-1-phosphate receptor 3 | ENSG00000213694 | S1PR3 | chr9:88991447-89005010:+ | 10 | 12 |
C-X-C motif chemokine receptor 3 | ENSG00000186810 | CXCR3 | chrX:71615916-71618517:- | 11 | 14 |
CD58 molecule | ENSG00000116815 | CD58 | chr1:116514535-116571039:- | 10 | 16.5 |
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