GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
CEA cell adhesion molecule 5ENSG00000105388CEACAM5chr19:41576273-41729798:+1113
reticulon 4 receptorENSG00000040608RTN4Rchr22:20241415-20283246:-1112.5
gamma-glutamyltransferase 5ENSG00000099998GGT5chr22:24219654-24245142:-1217
platelet activating factor receptorENSG00000169403PTAFRchr1:28147166-28193936:-1016
apelin receptorENSG00000134817APLNRchr11:57233577-57237314:-1116
C-X-C motif chemokine receptor 1ENSG00000163464CXCR1chr2:218162845-218166995:-1116
neuropeptide Y receptor Y1ENSG00000164128NPY1Rchr4:163323961-163344832:-1015
opioid receptor kappa 1ENSG00000082556OPRK1chr8:53225716-53251697:-1116
5-hydroxytryptamine receptor 2BENSG00000135914HTR2Bchr2:231108230-231125118:-1115
coagulation factor II thrombin receptorENSG00000181104F2Rchr5:76716043-76735781:+1117
angiotensin II receptor type 2ENSG00000180772AGTR2chrX:116170722-116174972:+1115
5-hydroxytryptamine receptor 7ENSG00000148680HTR7chr10:90740823-90857698:-1113
purinergic receptor P2Y11ENSG00000244165P2RY11chr19:10111538-10115372:+1014
ATP binding cassette subfamily G member 2 (Junior blood group)ENSG00000118777ABCG2chr4:88090264-88231322:-1015.5
adhesion G protein-coupled receptor L4ENSG00000162618ADGRL4chr1:78889764-79006718:-1114
semaphorin 4GENSG00000095539SEMA4Gchr10:100969518-100985871:+1113
fibroblast growth factor receptor 2ENSG00000066468FGFR2chr10:121478334-121598458:-1114
C-X-C motif chemokine receptor 5ENSG00000160683CXCR5chr11:118883766-118897799:+1114
lysophosphatidic acid receptor 5ENSG00000184574LPAR5chr12:6618835-6636447:-1013
chemerin chemokine-like receptor 1ENSG00000174600CMKLR1chr12:108288044-108339341:-1012

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