GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
ATP synthase F1 subunit alphaENSG00000152234ATP5A1chr18:46080248-46104334:-411
adaptor related protein complex 2 subunit sigma 1ENSG00000042753AP2S1chr19:46838136-46850992:-48
syntrophin gamma 2ENSG00000172554SNTG2chr2:950868-1367613:+44
pleckstrin and Sec7 domain containing 4ENSG00000125637PSD4chr2:113157325-113209396:+45
oxysterol binding protein like 6ENSG00000079156OSBPL6chr2:178194481-178402891:+44
syndecan binding protein 2ENSG00000125775SDCBP2chr20:1309909-1329239:-44
signal regulatory protein deltaENSG00000125900SIRPDchr20:1534251-1558843:-44.5
par-6 family cell polarity regulator betaENSG00000124171PARD6Bchr20:50731544-50756795:+44
protein tyrosine kinase 6ENSG00000101213PTK6chr20:63528001-63537370:-44
synaptosome associated protein 29ENSG00000099940SNAP29chr22:20858983-20891218:+46
protein interacting with PRKCA 1ENSG00000100151PICK1chr22:38056311-38075701:+44
semaphorin 3BENSG00000012171SEMA3Bchr3:50267558-50277546:+44.5
ADP ribosylation factor like GTPase 6ENSG00000113966ARL6chr3:97764521-97801242:+44
LIM domain containing preferred translocation partner in lipomaENSG00000145012LPPchr3:188153284-188890671:+47
toll like receptor adaptor molecule 2ENSG00000243414TICAM2chr5:115578650-115602479:-45
CDC42 small effector 2ENSG00000158985CDC42SE2chr5:131245493-131398447:+46
myosin VIENSG00000196586MYO6chr6:75749192-75919537:+48
interleukin 22 receptor subunit alpha 2ENSG00000164485IL22RA2chr6:137143820-137173648:-44
ADP ribosylation factor like GTPase 4AENSG00000122644ARL4Achr7:12686856-12690934:+44
myosin IGENSG00000136286MYO1Gchr7:44962662-44979098:-46

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