GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
ATP synthase F1 subunit alpha | ENSG00000152234 | ATP5A1 | chr18:46080248-46104334:- | 4 | 11 |
adaptor related protein complex 2 subunit sigma 1 | ENSG00000042753 | AP2S1 | chr19:46838136-46850992:- | 4 | 8 |
syntrophin gamma 2 | ENSG00000172554 | SNTG2 | chr2:950868-1367613:+ | 4 | 4 |
pleckstrin and Sec7 domain containing 4 | ENSG00000125637 | PSD4 | chr2:113157325-113209396:+ | 4 | 5 |
oxysterol binding protein like 6 | ENSG00000079156 | OSBPL6 | chr2:178194481-178402891:+ | 4 | 4 |
syndecan binding protein 2 | ENSG00000125775 | SDCBP2 | chr20:1309909-1329239:- | 4 | 4 |
signal regulatory protein delta | ENSG00000125900 | SIRPD | chr20:1534251-1558843:- | 4 | 4.5 |
par-6 family cell polarity regulator beta | ENSG00000124171 | PARD6B | chr20:50731544-50756795:+ | 4 | 4 |
protein tyrosine kinase 6 | ENSG00000101213 | PTK6 | chr20:63528001-63537370:- | 4 | 4 |
synaptosome associated protein 29 | ENSG00000099940 | SNAP29 | chr22:20858983-20891218:+ | 4 | 6 |
protein interacting with PRKCA 1 | ENSG00000100151 | PICK1 | chr22:38056311-38075701:+ | 4 | 4 |
semaphorin 3B | ENSG00000012171 | SEMA3B | chr3:50267558-50277546:+ | 4 | 4.5 |
ADP ribosylation factor like GTPase 6 | ENSG00000113966 | ARL6 | chr3:97764521-97801242:+ | 4 | 4 |
LIM domain containing preferred translocation partner in lipoma | ENSG00000145012 | LPP | chr3:188153284-188890671:+ | 4 | 7 |
toll like receptor adaptor molecule 2 | ENSG00000243414 | TICAM2 | chr5:115578650-115602479:- | 4 | 5 |
CDC42 small effector 2 | ENSG00000158985 | CDC42SE2 | chr5:131245493-131398447:+ | 4 | 6 |
myosin VI | ENSG00000196586 | MYO6 | chr6:75749192-75919537:+ | 4 | 8 |
interleukin 22 receptor subunit alpha 2 | ENSG00000164485 | IL22RA2 | chr6:137143820-137173648:- | 4 | 4 |
ADP ribosylation factor like GTPase 4A | ENSG00000122644 | ARL4A | chr7:12686856-12690934:+ | 4 | 4 |
myosin IG | ENSG00000136286 | MYO1G | chr7:44962662-44979098:- | 4 | 6 |
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