GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
synaptotagmin like 1 | ENSG00000142765 | SYTL1 | chr1:27342020-27353937:+ | 4 | 4 |
regulator of G protein signaling 1 | ENSG00000090104 | RGS1 | chr1:192575727-192580031:+ | 4 | 4 |
regulator of G protein signaling 2 | ENSG00000116741 | RGS2 | chr1:192809039-192812283:+ | 4 | 4 |
calcium voltage-gated channel auxiliary subunit beta 2 | ENSG00000165995 | CACNB2 | chr10:18140677-18541869:+ | 4 | 4 |
RAB11 family interacting protein 2 | ENSG00000107560 | RAB11FIP2 | chr10:118004916-118046603:- | 4 | 5 |
caveolae associated protein 3 | ENSG00000170955 | PRKCDBP | chr11:6318946-6320647:- | 4 | 6 |
lin-7 homolog C, crumbs cell polarity complex component | ENSG00000148943 | LIN7C | chr11:27494576-27506773:- | 4 | 6 |
RAB35, member RAS oncogene family | ENSG00000111737 | RAB35 | chr12:120095095-120117502:- | 4 | 9 |
APC membrane recruitment protein 2 | ENSG00000165566 | AMER2 | chr13:25161684-25172288:- | 4 | 4 |
pleckstrin 2 | ENSG00000100558 | PLEK2 | chr14:67386983-67412200:- | 4 | 4 |
SHC adaptor protein 4 | ENSG00000185634 | SHC4 | chr15:48823735-48963444:- | 4 | 4 |
ubiquitin specific peptidase 8 | ENSG00000138592 | USP8 | chr15:50424380-50514419:+ | 4 | 6 |
FES proto-oncogene, tyrosine kinase | ENSG00000182511 | FES | chr15:90883695-90895776:+ | 4 | 5 |
Bardet-Biedl syndrome 2 | ENSG00000125124 | BBS2 | chr16:56466836-56520283:- | 4 | 5 |
glutamic-oxaloacetic transaminase 2 | ENSG00000125166 | GOT2 | chr16:58707131-58734357:- | 4 | 10 |
ArfGAP with dual PH domains 2 | ENSG00000184060 | ADAP2 | chr17:30906344-30959322:+ | 4 | 5 |
ADP ribosylation factor like GTPase 4D | ENSG00000175906 | ARL4D | chr17:43398959-43401137:+ | 4 | 4 |
G protein subunit gamma transducin 2 | ENSG00000167083 | GNGT2 | chr17:49202791-49210574:- | 4 | 4 |
protein phosphatase 1 regulatory subunit 9B | ENSG00000108819 | PPP1R9B | chr17:50133735-50150630:- | 4 | 6 |
Rac family small GTPase 3 | ENSG00000169750 | RAC3 | chr17:82031624-82034204:+ | 4 | 8 |
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