GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
abl interactor 1 | ENSG00000136754 | ABI1 | chr10:26746593-26861087:- | 4 | 6.5 |
neuralized E3 ubiquitin protein ligase 1 | ENSG00000107954 | NEURL1 | chr10:103493979-103592552:+ | 4 | 4 |
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha | ENSG00000011405 | PIK3C2A | chr11:17077730-17207983:- | 4 | 6 |
Bardet-Biedl syndrome 1 | ENSG00000174483 | BBS1 | chr11:66510606-66533627:+ | 4 | 5 |
phosphodiesterase 2A | ENSG00000186642 | PDE2A | chr11:72576141-72674591:- | 4 | 4 |
protein arginine methyltransferase 8 | ENSG00000111218 | PRMT8 | chr12:3381349-3593973:+ | 4 | 4 |
discs large MAGUK scaffold protein 4 | ENSG00000132535 | DLG4 | chr17:7189890-7219702:- | 4 | 4.5 |
prolyl 4-hydroxylase subunit beta | ENSG00000185624 | P4HB | chr17:81843159-81860694:- | 4 | 10 |
dynamin 2 | ENSG00000079805 | DNM2 | chr19:10718079-10833488:+ | 4 | 10 |
family with sequence similarity 126 member B | ENSG00000155744 | FAM126B | chr2:200973718-201071671:- | 4 | 4 |
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 | ENSG00000124126 | PREX1 | chr20:48624252-48827883:- | 4 | 6 |
immunoglobulin lambda like polypeptide 5 | ENSG00000254709 | IGLL5 | chr22:22734620-22896107:+ | 4 | 4.5 |
FER tyrosine kinase | ENSG00000151422 | FER | chr5:108747822-109196841:+ | 4 | 5 |
TUB like protein 1 | ENSG00000112041 | TULP1 | chr6:35497874-35512938:- | 4 | 5 |
LanC like 2 | ENSG00000132434 | LANCL2 | chr7:55365448-55433742:+ | 4 | 7 |
SH2B adaptor protein 2 | ENSG00000160999 | SH2B2 | chr7:102285091-102321711:+ | 4 | 4.5 |
nitric oxide synthase 3 | ENSG00000164867 | NOS3 | chr7:150990995-151014588:+ | 4 | 4 |
protein tyrosine kinase 2 | ENSG00000169398 | PTK2 | chr8:140657900-141002216:- | 4 | 6 |
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 | ENSG00000277494 | GPIHBP1 | chr8:143213193-143217170:+ | 4 | 4 |
MAPK associated protein 1 | ENSG00000119487 | MAPKAP1 | chr9:125437393-125707234:- | 4 | 5 |
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