GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
calcium/calmodulin dependent protein kinase II gamma | ENSG00000148660 | CAMK2G | chr10:73812501-73874591:- | 4 | 8.5 |
sterol-C5-desaturase | ENSG00000109929 | SC5D | chr11:121292453-121308694:+ | 4 | 5.5 |
junctophilin 4 | ENSG00000092051 | JPH4 | chr14:23568035-23578800:- | 4 | 5 |
zinc finger DHHC-type palmitoyltransferase 22 | ENSG00000177108 | ZDHHC22 | chr14:77131270-77142734:- | 4 | 5.5 |
ryanodine receptor 3 | ENSG00000198838 | RYR3 | chr15:33310962-33866102:+ | 4 | 6.5 |
phosphatidylinositol glycan anchor biosynthesis class B | ENSG00000069943 | PIGB | chr15:55318960-55355648:+ | 4 | 7.5 |
NODAL modulator 1 | ENSG00000103512 | NOMO1 | chr16:14833681-14896160:+ | 4 | 8 |
ATPase secretory pathway Ca2+ transporting 2 | ENSG00000064270 | ATP2C2 | chr16:84368527-84464187:+ | 4 | 5.5 |
phospholipid scramblase 3 | ENSG00000187838 | TMEM256-PLSCR3 | chr17:7389727-7394843:- | 4 | 7.5 |
secretory carrier membrane protein 4 | ENSG00000227500 | SCAMP4 | chr19:1905214-1926013:+ | 4 | 8.5 |
ryanodine receptor 1 | ENSG00000196218 | RYR1 | chr19:38433699-38587564:+ | 4 | 6.5 |
NCK associated protein 1 | ENSG00000061676 | NCKAP1 | chr2:182909115-183038858:- | 4 | 7 |
Ig-like domain-containing protein | ENSG00000277117 | ICOSLG | chr21:5022493-5040666:+ | 4 | 6.5 |
lipase maturation factor 2 | ENSG00000100258 | LMF2 | chr22:50502949-50507691:- | 4 | 10.5 |
phospholipid scramblase 4 | ENSG00000114698 | PLSCR4 | chr3:146192339-146251179:- | 4 | 6 |
steroid 5 alpha-reductase 3 | ENSG00000128039 | SRD5A3 | chr4:55346109-55373096:+ | 4 | 6.5 |
secretory carrier membrane protein 1 | ENSG00000085365 | SCAMP1 | chr5:78360583-78479071:+ | 4 | 7.5 |
monooxygenase DBH like 1 | ENSG00000079931 | MOXD1 | chr6:132296055-132401545:- | 4 | 9 |
dpy-19 like 4 | ENSG00000156162 | DPY19L4 | chr8:94719703-94793836:+ | 4 | 6.5 |
ryanodine receptor 2 | ENSG00000198626 | RYR2 | chr1:237042205-237833988:+ | 4 | 5.5 |
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