GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
Lck interacting transmembrane adaptor 1 | ENSG00000203896 | LIME1 | chr20:63736283-63739103:+ | 4 | 5.5 |
potassium voltage-gated channel subfamily H member 8 | ENSG00000183960 | KCNH8 | chr3:19148454-19535646:+ | 4 | 6.5 |
solute carrier family 38 member 3 | ENSG00000188338 | SLC38A3 | chr3:50205246-50221486:+ | 4 | 5.5 |
solute carrier family 35 member A5 | ENSG00000138459 | SLC35A5 | chr3:112561709-112585577:+ | 4 | 5.5 |
popeye domain containing 2 | ENSG00000121577 | POPDC2 | chr3:119636457-119665324:- | 4 | 5.5 |
microsomal glutathione S-transferase 2 | ENSG00000085871 | MGST2 | chr4:139665768-139740745:+ | 4 | 7.5 |
solute carrier family 30 member 5 | ENSG00000145740 | SLC30A5 | chr5:69093646-69131069:+ | 4 | 6.5 |
potassium calcium-activated channel subfamily N member 2 | ENSG00000080709 | KCNN2 | chr5:114360945-114496500:+ | 4 | 5.5 |
gap junction protein alpha 10 | ENSG00000135355 | GJA10 | chr6:89894469-89896120:+ | 4 | 5.5 |
tumor suppressor candidate 3 | ENSG00000104723 | TUSC3 | chr8:15417215-15766649:+ | 4 | 6.5 |
phospholipid phosphatase 5 | ENSG00000147535 | PPAPDC1B | chr8:38263130-38269243:- | 4 | 5.5 |
potassium voltage-gated channel modifier subfamily S member 2 | ENSG00000156486 | KCNS2 | chr8:98427022-98432848:+ | 4 | 5.5 |
solute carrier family 30 member 8 | ENSG00000164756 | SLC30A8 | chr8:116950273-117176714:+ | 4 | 5.5 |
phospholipid phosphatase related 1 | ENSG00000148123 | RP11-35N6.1 | chr9:101028709-101325135:+ | 4 | 5.5 |
myomaker, myoblast fusion factor | ENSG00000187616 | TMEM8C | chr9:133514586-133528612:- | 4 | 5.5 |
membrane magnesium transporter 1 | ENSG00000169446 | MMGT1 | chrX:135962070-135974063:- | 4 | 7.5 |
B cell receptor associated protein 31 | ENSG00000185825 | BCAP31 | chrX:153700497-153724697:- | 4 | 11.5 |
solute carrier family 30 member 2 | ENSG00000158014 | SLC30A2 | chr1:26037252-26046133:- | 4 | 5.5 |
ceramide synthase 2 | ENSG00000143418 | CERS2 | chr1:150960583-150975004:- | 4 | 9.5 |
odr-4 GPCR localization factor homolog | ENSG00000157181 | C1orf27 | chr1:186375758-186421378:+ | 4 | 7.5 |
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