GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
purinergic receptor P2X 4ENSG00000135124P2RX4chr12:121209857-121234106:+1216.5
scavenger receptor class B member 1ENSG00000073060SCARB1chr12:124776856-124882668:-1118.5
solute carrier family 7 member 1ENSG00000139514SLC7A1chr13:29509410-29595688:-1118.5
FRAS1 related extracellular matrix 2ENSG00000150893FREM2chr13:38687129-38887131:+1112.5
semaphorin 7A (John Milton Hagen blood group)ENSG00000138623SEMA7Achr15:74409289-74434467:-1219
ATP binding cassette subfamily A member 7ENSG00000064687ABCA7chr19:1040101-1065572:+1115.5
prominin 2ENSG00000155066PROM2chr2:95274453-95291308:+1213.5
cyclin and CBS domain divalent metal cation transport mediator 4ENSG00000158158CNNM4chr2:96760902-96811891:+1118.5
plexin B2ENSG00000196576PLXNB2chr22:50274979-50307627:-1220
solute carrier organic anion transporter family member 4C1ENSG00000173930SLCO4C1chr5:102233986-102296549:-1213.5
CD74 moleculeENSG00000019582CD74chr5:150401637-150412929:-1116
solute carrier family 7 member 2ENSG00000003989SLC7A2chr8:17497088-17570573:+1113.5
leucine rich repeat containing 26ENSG00000184709LRRC26chr9:137168758-137170051:-1213.5
plexin A3ENSG00000130827PLXNA3chrX:154458281-154477779:+1215
agrinENSG00000188157AGRNchr1:1020123-1056118:+1116.5
acid sensing ion channel subunit 1ENSG00000110881ASIC1chr12:50057548-50083611:+1112
CEA cell adhesion molecule 6ENSG00000086548CEACAM6chr19:41750977-41772208:+1113
solute carrier family 39 member 10ENSG00000196950SLC39A10chr2:195575977-195737702:+1219.5
GDNF family receptor alpha 3ENSG00000146013GFRA3chr5:138252379-138274671:-1215
transmembrane protein 245ENSG00000106771TMEM245chr9:109015152-109119945:-1114.5

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