GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
vesicle associated membrane protein 7ENSG00000124333VAMP7chrX:155881293-155943769:+49.5
Rh blood group D antigenENSG00000187010RHDchr1:25272393-25330445:+45.5
XK related 8ENSG00000158156XKR8chr1:27959462-27968096:+46.5
erythrocyte membrane protein band 4.1ENSG00000159023EPB41chr1:28887091-29120046:+48.5
solute carrier family 30 member 10ENSG00000196660SLC30A10chr1:219685427-219958647:-45.5
solute carrier family 39 member 12ENSG00000148482SLC39A12chr10:17951839-18043292:+45.5
solute carrier family 29 member 3ENSG00000198246SLC29A3chr10:71319258-71363385:+46.5
calcium homeostasis modulator family member 2ENSG00000138172CALHM2chr10:103446786-103452402:-46.5
interferon induced transmembrane protein 2ENSG00000185201IFITM2chr11:307631-315272:+48.5
potassium voltage-gated channel subfamily A member 4ENSG00000182255KCNA4chr11:30009741-30017023:-45.5
retinal outer segment membrane protein 1ENSG00000149489ROM1chr11:62611722-62615120:+45.5
claudin 25ENSG00000228607CLDN25chr11:113779747-113780500:+45.5
ALG10 alpha-1,2-glucosyltransferase BENSG00000175548ALG10Bchr12:38316578-38329728:+45.5
ATPase phospholipid transporting 11AENSG00000068650ATP11Achr13:112690329-112887168:+48.5
abhydrolase domain containing 2, acylglycerol lipaseENSG00000140526ABHD2chr15:89087459-89202360:+45
synaptic vesicle glycoprotein 2BENSG00000185518SV2Bchr15:91099950-91301309:+45.5
TNF receptor superfamily member 12AENSG00000006327TNFRSF12Achr16:3018445-3022383:+35.5
transient receptor potential cation channel subfamily V member 1ENSG00000196689TRPV1chr17:3565444-3597098:-45.5
synaptotagmin 4ENSG00000132872SYT4chr18:43267878-43277650:-46.5
natural killer cell granule protein 7ENSG00000105374NKG7chr19:51371606-51372715:-45.5

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