GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
phospholipase C delta 3 | ENSG00000161714 | PLCD3 | chr17:45108967-45133354:- | 4 | 6 |
lactoperoxidase | ENSG00000167419 | LPO | chr17:58218548-58268518:+ | 4 | 4 |
clathrin heavy chain | ENSG00000141367 | CLTC | chr17:59619689-59696956:+ | 4 | 11 |
cytokine receptor like factor 1 | ENSG00000006016 | CRLF1 | chr19:18572220-18607741:- | 5 | 5 |
calpain small subunit 1 | ENSG00000126247 | CAPNS1 | chr19:36139575-36150353:+ | 4 | 9 |
T cell receptor beta variable 2 | ENSG00000226660 | TRBV2 | chr7:142300924-142301432:+ | 4 | 4 |
ADAM metallopeptidase with thrombospondin type 1 motif 7 | ENSG00000136378 | ADAMTS7 | chr15:78759203-78811431:- | 4 | 4 |
heat shock protein family D (Hsp60) member 1 | ENSG00000144381 | HSPD1 | chr2:197486581-197516737:- | 5 | 12 |
mucolipin 3 | ENSG00000055732 | MCOLN3 | chr1:85018082-85048499:- | 4 | 7.5 |
nucleoporin 210 | ENSG00000132182 | NUP210 | chr3:13316235-13420309:- | 4 | 10 |
interleukin 22 receptor subunit alpha 1 | ENSG00000142677 | IL22RA1 | chr1:24119771-24143121:- | 4 | 5.5 |
gap junction protein alpha 9 | ENSG00000131233 | GJA9 | chr1:38874451-38881587:- | 4 | 6 |
ATPase phospholipid transporting 8B2 | ENSG00000143515 | ATP8B2 | chr1:154325553-154351307:+ | 4 | 6.5 |
syntaxin 6 | ENSG00000135823 | STX6 | chr1:180972712-181023121:- | 4 | 8.5 |
potassium sodium-activated channel subfamily T member 2 | ENSG00000162687 | KCNT2 | chr1:196225779-196609225:- | 4 | 5.5 |
potassium voltage-gated channel subfamily H member 1 | ENSG00000143473 | KCNH1 | chr1:210678315-211134115:- | 4 | 5.5 |
synaptotagmin 15 | ENSG00000204176 | SYT15 | chr10:46578217-46594173:+ | 4 | 6.5 |
interferon induced transmembrane protein 5 | ENSG00000206013 | IFITM5 | chr11:298200-299526:- | 4 | 5.5 |
syntaxin 3 | ENSG00000166900 | STX3 | chr11:59713456-59805882:+ | 4 | 7.5 |
protein tyrosine phosphatase receptor type C associated protein | ENSG00000213402 | PTPRCAP | chr11:67435510-67438067:- | 4 | 6.5 |
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