GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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| HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
| receptor interacting serine/threonine kinase 1 | ENSG00000137275 | RIPK1 | chr6:3063991-3115187:+ | 4 | 5 |
| butyrophilin subfamily 2 member A3, pseudogene | ENSG00000124549 | BTN2A3P | chr6:26421391-26432383:+ | 5 | 6 |
| erythrocyte membrane protein band 4.1 like 2 | ENSG00000079819 | EPB41L2 | chr6:130839347-131063322:- | 5 | 10 |
| RALBP1 associated Eps domain containing 1 | ENSG00000135597 | REPS1 | chr6:138903493-138988261:- | 4 | 5 |
| RAS like proto-oncogene A | ENSG00000006451 | RALA | chr7:39623483-39708124:+ | 4 | 7 |
| leucine zipper tumor suppressor 1 | ENSG00000061337 | LZTS1 | chr8:20246165-20303963:- | 4 | 4 |
| caveolae associated protein 4 | ENSG00000170681 | MURC | chr9:100578079-100587906:+ | 4 | 4 |
| paralemmin 2 | ENSG00000243444 | PALM2 | chr9:109640788-109946703:+ | 4 | 5 |
| BMX non-receptor tyrosine kinase | ENSG00000102010 | BMX | chrX:15464246-15556529:+ | 4 | 4 |
| ecto-NOX disulfide-thiol exchanger 2 | ENSG00000165675 | ENOX2 | chrX:130623369-130903317:- | 4 | 4 |
| angiopoietin like 3 | ENSG00000132855 | ANGPTL3 | chr1:62597487-62606159:+ | 4 | 4 |
| olfactomedin 4 | ENSG00000102837 | OLFM4 | chr13:53028759-53052057:+ | 4 | 4 |
| T cell receptor alpha variable 3 (gene/pseudogene) | ENSG00000211777 | TRAV3 | chr14:21723713-21724321:+ | 4 | 4 |
| galectin 3 | ENSG00000131981 | LGALS3 | chr14:55124110-55145413:+ | 4 | 9 |
| immunoglobulin heavy constant gamma 4 (G4m marker) | ENSG00000211892 | IGHG4 | chr14:105624341-105626066:- | 5 | 5 |
| immunoglobulin heavy constant gamma 2 (G2m marker) | ENSG00000211893 | IGHG2 | chr14:105643052-105644790:- | 5 | 6 |
| immunoglobulin heavy constant gamma 1 (G1m marker) | ENSG00000211896 | IGHG1 | chr14:105668113-106538344:- | 5 | 8 |
| immunoglobulin heavy constant alpha 1 | ENSG00000211895 | IGHA1 | chr14:105707118-105708665:- | 5 | 7 |
| cerebellin 1 precursor | ENSG00000102924 | CBLN1 | chr16:49277917-49281831:- | 4 | 4 |
| polycystin 1 like 2 (gene/pseudogene) | ENSG00000166473 | PKD1L2 | chr16:81100875-81220370:- | 4 | 4 |
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