GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
sialic acid binding Ig like lectin 16 (gene/pseudogene)ENSG00000161643SIGLEC16chr19:49969673-49975814:+44
ras homolog family member BENSG00000143878RHOBchr2:20447074-20449445:+58
caveolae associated protein 2ENSG00000168497SDPRchr2:191834302-191847255:-46
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1ENSG00000173166RAPH1chr2:203394345-203535410:-45
angio associated migratory cell proteinENSG00000127837AAMPchr2:218264123-218270257:-45
beaded filament structural protein 1ENSG00000125864BFSP1chr20:17493905-17569220:-44
TIAM Rac1 associated GEF 1ENSG00000156299TIAM1chr21:31118416-31559977:-45
thrombospondin type laminin G domain and EAR repeatsENSG00000175894TSPEARchr21:44497892-44711580:-44.5
RASD family member 2ENSG00000100302RASD2chr22:35540868-35554001:+44
protein kinase C and casein kinase substrate in neurons 2ENSG00000100266PACSIN2chr22:42835412-43015145:-58
ras homolog family member AENSG00000067560RHOAchr3:49359145-49412998:-510
PX domain containing serine/threonine kinase likeENSG00000168297PXKchr3:58332880-58426126:+44
membrane associated guanylate kinase, WW and PDZ domain containing 1ENSG00000151276MAGI1chr3:65353525-66038834:-45
transmembrane protein 30C, pseudogeneENSG00000235156TMEM30Cchr3:100185824-100194191:+55
beaded filament structural protein 2ENSG00000170819BFSP2chr3:133399995-133475222:+44
exocyst complex component 1ENSG00000090989EXOC1chr4:55853616-55905034:+57
ubiquitin conjugating enzyme E2 D3ENSG00000109332UBE2D3chr4:102794383-102868896:-47
kallikrein B1ENSG00000164344KLKB1chr4:186208979-186258471:+46
diaphanous related formin 1ENSG00000131504DIAPH1chr5:141515016-141619055:-410
G protein regulated inducer of neurite outgrowth 1ENSG00000169258GPRIN1chr5:176595802-176610133:-45

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