GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
sialic acid binding Ig like lectin 16 (gene/pseudogene) | ENSG00000161643 | SIGLEC16 | chr19:49969673-49975814:+ | 4 | 4 |
ras homolog family member B | ENSG00000143878 | RHOB | chr2:20447074-20449445:+ | 5 | 8 |
caveolae associated protein 2 | ENSG00000168497 | SDPR | chr2:191834302-191847255:- | 4 | 6 |
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | ENSG00000173166 | RAPH1 | chr2:203394345-203535410:- | 4 | 5 |
angio associated migratory cell protein | ENSG00000127837 | AAMP | chr2:218264123-218270257:- | 4 | 5 |
beaded filament structural protein 1 | ENSG00000125864 | BFSP1 | chr20:17493905-17569220:- | 4 | 4 |
TIAM Rac1 associated GEF 1 | ENSG00000156299 | TIAM1 | chr21:31118416-31559977:- | 4 | 5 |
thrombospondin type laminin G domain and EAR repeats | ENSG00000175894 | TSPEAR | chr21:44497892-44711580:- | 4 | 4.5 |
RASD family member 2 | ENSG00000100302 | RASD2 | chr22:35540868-35554001:+ | 4 | 4 |
protein kinase C and casein kinase substrate in neurons 2 | ENSG00000100266 | PACSIN2 | chr22:42835412-43015145:- | 5 | 8 |
ras homolog family member A | ENSG00000067560 | RHOA | chr3:49359145-49412998:- | 5 | 10 |
PX domain containing serine/threonine kinase like | ENSG00000168297 | PXK | chr3:58332880-58426126:+ | 4 | 4 |
membrane associated guanylate kinase, WW and PDZ domain containing 1 | ENSG00000151276 | MAGI1 | chr3:65353525-66038834:- | 4 | 5 |
transmembrane protein 30C, pseudogene | ENSG00000235156 | TMEM30C | chr3:100185824-100194191:+ | 5 | 5 |
beaded filament structural protein 2 | ENSG00000170819 | BFSP2 | chr3:133399995-133475222:+ | 4 | 4 |
exocyst complex component 1 | ENSG00000090989 | EXOC1 | chr4:55853616-55905034:+ | 5 | 7 |
ubiquitin conjugating enzyme E2 D3 | ENSG00000109332 | UBE2D3 | chr4:102794383-102868896:- | 4 | 7 |
kallikrein B1 | ENSG00000164344 | KLKB1 | chr4:186208979-186258471:+ | 4 | 6 |
diaphanous related formin 1 | ENSG00000131504 | DIAPH1 | chr5:141515016-141619055:- | 4 | 10 |
G protein regulated inducer of neurite outgrowth 1 | ENSG00000169258 | GPRIN1 | chr5:176595802-176610133:- | 4 | 5 |
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