GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
ELKS/RAB6-interacting/CAST family member 1ENSG00000082805ERC1chr12:990509-1495933:+45
Rho family GTPase 1ENSG00000172602RND1chr12:48857145-48865898:-55
fibroblast growth factor receptor substrate 2ENSG00000166225FRS2chr12:69470349-69579789:+45
ankyrin repeat domain 13AENSG00000076513ANKRD13Achr12:109999186-110039763:+46
ecto-NOX disulfide-thiol exchanger 1ENSG00000120658ENOX1chr13:43213518-43786908:-44
sciellinENSG00000136155SCELchr13:77535674-77645263:+44
tetratricopeptide repeat domain 7BENSG00000165914TTC7Bchr14:90524564-90816479:-56
beta-2-microglobulinENSG00000166710B2Mchr15:44711477-44718877:+410
RAB11A, member RAS oncogene familyENSG00000103769RAB11Achr15:65726054-65891991:+511
par-6 family cell polarity regulator alphaENSG00000102981PARD6Achr16:67660946-67662778:+55
ras related dexamethasone induced 1ENSG00000108551RASD1chr17:17494437-17496395:-44
growth factor receptor bound protein 7ENSG00000141738GRB7chr17:39737927-39747291:+44
junction plakoglobinENSG00000173801JUPchr17:41754604-41786931:-510
exocyst complex component 7ENSG00000182473EXOC7chr17:76081017-76121576:-46
mindbomb E3 ubiquitin protein ligase 1ENSG00000101752MIB1chr18:21704957-21870957:+45
par-6 family cell polarity regulator gammaENSG00000178184PARD6Gchr18:80157232-80247546:-55
tight junction protein 3ENSG00000105289TJP3chr19:3708109-3750813:+55
calreticulinENSG00000179218CALRchr19:12938578-12944489:+411.5
paralemmin 3ENSG00000187867PALM3chr19:14053365-14059159:-44
RAB8A, member RAS oncogene familyENSG00000167461RAB8Achr19:16111629-16134234:+59

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