GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
ELKS/RAB6-interacting/CAST family member 1 | ENSG00000082805 | ERC1 | chr12:990509-1495933:+ | 4 | 5 |
Rho family GTPase 1 | ENSG00000172602 | RND1 | chr12:48857145-48865898:- | 5 | 5 |
fibroblast growth factor receptor substrate 2 | ENSG00000166225 | FRS2 | chr12:69470349-69579789:+ | 4 | 5 |
ankyrin repeat domain 13A | ENSG00000076513 | ANKRD13A | chr12:109999186-110039763:+ | 4 | 6 |
ecto-NOX disulfide-thiol exchanger 1 | ENSG00000120658 | ENOX1 | chr13:43213518-43786908:- | 4 | 4 |
sciellin | ENSG00000136155 | SCEL | chr13:77535674-77645263:+ | 4 | 4 |
tetratricopeptide repeat domain 7B | ENSG00000165914 | TTC7B | chr14:90524564-90816479:- | 5 | 6 |
beta-2-microglobulin | ENSG00000166710 | B2M | chr15:44711477-44718877:+ | 4 | 10 |
RAB11A, member RAS oncogene family | ENSG00000103769 | RAB11A | chr15:65726054-65891991:+ | 5 | 11 |
par-6 family cell polarity regulator alpha | ENSG00000102981 | PARD6A | chr16:67660946-67662778:+ | 5 | 5 |
ras related dexamethasone induced 1 | ENSG00000108551 | RASD1 | chr17:17494437-17496395:- | 4 | 4 |
growth factor receptor bound protein 7 | ENSG00000141738 | GRB7 | chr17:39737927-39747291:+ | 4 | 4 |
junction plakoglobin | ENSG00000173801 | JUP | chr17:41754604-41786931:- | 5 | 10 |
exocyst complex component 7 | ENSG00000182473 | EXOC7 | chr17:76081017-76121576:- | 4 | 6 |
mindbomb E3 ubiquitin protein ligase 1 | ENSG00000101752 | MIB1 | chr18:21704957-21870957:+ | 4 | 5 |
par-6 family cell polarity regulator gamma | ENSG00000178184 | PARD6G | chr18:80157232-80247546:- | 5 | 5 |
tight junction protein 3 | ENSG00000105289 | TJP3 | chr19:3708109-3750813:+ | 5 | 5 |
calreticulin | ENSG00000179218 | CALR | chr19:12938578-12944489:+ | 4 | 11.5 |
paralemmin 3 | ENSG00000187867 | PALM3 | chr19:14053365-14059159:- | 4 | 4 |
RAB8A, member RAS oncogene family | ENSG00000167461 | RAB8A | chr19:16111629-16134234:+ | 5 | 9 |
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