GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
RAB25, member RAS oncogene familyENSG00000132698RAB25chr1:156061160-156070514:+56
tenascin NENSG00000120332TNNchr1:175067858-175148066:+44
ADP ribosylation factor 1ENSG00000143761ARF1chr1:228082660-228099212:+58
butyrophilin like 10ENSG00000215811BTNL10chr1:228508655-228512305:-55
amyloid beta precursor protein binding family B member 1 interacting proteinENSG00000077420APBB1IPchr10:26438203-26567803:+48
par-3 family cell polarity regulatorENSG00000148498PARD3chr10:34109560-34815325:-56
DnaJ heat shock protein family (Hsp40) member C9ENSG00000213551DNAJC9chr10:73183362-73248862:-46
discs large MAGUK scaffold protein 5ENSG00000151208DLG5chr10:77790791-77926526:-45
interferon induced protein with tetratricopeptide repeats 5ENSG00000152778IFIT5chr10:89414586-89421001:+45
sorbin and SH3 domain containing 1ENSG00000095637SORBS1chr10:95311771-95561414:-45
B cell linkerENSG00000095585BLNKchr10:96191702-96271587:-44
pleckstrin and Sec7 domain containingENSG00000059915PSDchr10:102402617-102421539:-44
EPS8 like 2ENSG00000177106EPS8L2chr11:694438-727727:+57
toll interacting proteinENSG00000078902TOLLIPchr11:1274371-1309654:-45
integrin linked kinaseENSG00000166333ILKchr11:6603708-6610874:+47
tumor susceptibility 101ENSG00000074319TSG101chr11:18468336-18527232:-46
protein kinase C and casein kinase substrate in neurons 3ENSG00000165912PACSIN3chr11:47177525-47186443:-57
olfactory receptor family 8 subfamily J member 2 (gene/pseudogene)ENSG00000254658OR8J2chr11:56210873-56211820:-44.5
FCH and double SH3 domains 2ENSG00000137478FCHSD2chr11:72836745-73142261:-56
discs large MAGUK scaffold protein 2ENSG00000150672DLG2chr11:83455012-85627922:-55

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