GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
RAB25, member RAS oncogene family | ENSG00000132698 | RAB25 | chr1:156061160-156070514:+ | 5 | 6 |
tenascin N | ENSG00000120332 | TNN | chr1:175067858-175148066:+ | 4 | 4 |
ADP ribosylation factor 1 | ENSG00000143761 | ARF1 | chr1:228082660-228099212:+ | 5 | 8 |
butyrophilin like 10 | ENSG00000215811 | BTNL10 | chr1:228508655-228512305:- | 5 | 5 |
amyloid beta precursor protein binding family B member 1 interacting protein | ENSG00000077420 | APBB1IP | chr10:26438203-26567803:+ | 4 | 8 |
par-3 family cell polarity regulator | ENSG00000148498 | PARD3 | chr10:34109560-34815325:- | 5 | 6 |
DnaJ heat shock protein family (Hsp40) member C9 | ENSG00000213551 | DNAJC9 | chr10:73183362-73248862:- | 4 | 6 |
discs large MAGUK scaffold protein 5 | ENSG00000151208 | DLG5 | chr10:77790791-77926526:- | 4 | 5 |
interferon induced protein with tetratricopeptide repeats 5 | ENSG00000152778 | IFIT5 | chr10:89414586-89421001:+ | 4 | 5 |
sorbin and SH3 domain containing 1 | ENSG00000095637 | SORBS1 | chr10:95311771-95561414:- | 4 | 5 |
B cell linker | ENSG00000095585 | BLNK | chr10:96191702-96271587:- | 4 | 4 |
pleckstrin and Sec7 domain containing | ENSG00000059915 | PSD | chr10:102402617-102421539:- | 4 | 4 |
EPS8 like 2 | ENSG00000177106 | EPS8L2 | chr11:694438-727727:+ | 5 | 7 |
toll interacting protein | ENSG00000078902 | TOLLIP | chr11:1274371-1309654:- | 4 | 5 |
integrin linked kinase | ENSG00000166333 | ILK | chr11:6603708-6610874:+ | 4 | 7 |
tumor susceptibility 101 | ENSG00000074319 | TSG101 | chr11:18468336-18527232:- | 4 | 6 |
protein kinase C and casein kinase substrate in neurons 3 | ENSG00000165912 | PACSIN3 | chr11:47177525-47186443:- | 5 | 7 |
olfactory receptor family 8 subfamily J member 2 (gene/pseudogene) | ENSG00000254658 | OR8J2 | chr11:56210873-56211820:- | 4 | 4.5 |
FCH and double SH3 domains 2 | ENSG00000137478 | FCHSD2 | chr11:72836745-73142261:- | 5 | 6 |
discs large MAGUK scaffold protein 2 | ENSG00000150672 | DLG2 | chr11:83455012-85627922:- | 5 | 5 |
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