GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
ArfGAP with dual PH domains 1ENSG00000105963ADAP1chr7:897901-955407:-56.5
EFR3 homolog AENSG00000132294EFR3Achr8:131904088-132013642:+59.5
phospholipase A2 group IIAENSG00000188257PLA2G2Achr1:19975431-19980416:-45.5
phospholipase A2 group IIFENSG00000158786PLA2G2Fchr1:20139326-20150386:+44.5
PATJ crumbs cell polarity complex componentENSG00000132849INADLchr1:61742477-62163920:+46.5
IKBKB interacting proteinENSG00000166130IKBIPchr12:98613405-98645113:-49.5
protein kinase D1ENSG00000184304PRKD1chr14:29576479-30191898:-45.5
scavenger receptor class F member 1ENSG00000074660SCARF1chr17:1633858-1645747:-45.5
arachidonate 15-lipoxygenase type BENSG00000179593ALOX15Bchr17:8039017-8049134:+46
C1q and TNF related 1ENSG00000173918C1QTNF1chr17:79022814-79049788:+45
pleckstrin homology, MyTH4 and FERM domain containing H2ENSG00000152527PLEKHH2chr2:43637273-43767987:+44.5
beta-1,4-galactosyltransferase 5ENSG00000158470B4GALT5chr20:49632945-49713878:-46
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferaseENSG00000100060MFNGchr22:37469063-37486401:-45.5
protein tyrosine phosphatase non-receptor type 13ENSG00000163629PTPN13chr4:86594315-86815171:+45.5
PDZ and LIM domain 5ENSG00000163110PDLIM5chr4:94451857-94668227:+47.5
laeverinENSG00000172901LVRNchr5:115962454-116027619:+56
small ArfGAP 1ENSG00000112305SMAP1chr6:70667776-70862015:+47
RAS p21 protein activator 4BENSG00000170667RASA4Bchr7:102482445-102517781:-55.5
chondroitin polymerizing factor 2ENSG00000033100CHPF2chr7:151232489-151238827:+45.5
stomatin like 2ENSG00000165283STOML2chr9:35099776-35103195:-410.5

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