GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
ArfGAP with dual PH domains 1 | ENSG00000105963 | ADAP1 | chr7:897901-955407:- | 5 | 6.5 |
EFR3 homolog A | ENSG00000132294 | EFR3A | chr8:131904088-132013642:+ | 5 | 9.5 |
phospholipase A2 group IIA | ENSG00000188257 | PLA2G2A | chr1:19975431-19980416:- | 4 | 5.5 |
phospholipase A2 group IIF | ENSG00000158786 | PLA2G2F | chr1:20139326-20150386:+ | 4 | 4.5 |
PATJ crumbs cell polarity complex component | ENSG00000132849 | INADL | chr1:61742477-62163920:+ | 4 | 6.5 |
IKBKB interacting protein | ENSG00000166130 | IKBIP | chr12:98613405-98645113:- | 4 | 9.5 |
protein kinase D1 | ENSG00000184304 | PRKD1 | chr14:29576479-30191898:- | 4 | 5.5 |
scavenger receptor class F member 1 | ENSG00000074660 | SCARF1 | chr17:1633858-1645747:- | 4 | 5.5 |
arachidonate 15-lipoxygenase type B | ENSG00000179593 | ALOX15B | chr17:8039017-8049134:+ | 4 | 6 |
C1q and TNF related 1 | ENSG00000173918 | C1QTNF1 | chr17:79022814-79049788:+ | 4 | 5 |
pleckstrin homology, MyTH4 and FERM domain containing H2 | ENSG00000152527 | PLEKHH2 | chr2:43637273-43767987:+ | 4 | 4.5 |
beta-1,4-galactosyltransferase 5 | ENSG00000158470 | B4GALT5 | chr20:49632945-49713878:- | 4 | 6 |
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | ENSG00000100060 | MFNG | chr22:37469063-37486401:- | 4 | 5.5 |
protein tyrosine phosphatase non-receptor type 13 | ENSG00000163629 | PTPN13 | chr4:86594315-86815171:+ | 4 | 5.5 |
PDZ and LIM domain 5 | ENSG00000163110 | PDLIM5 | chr4:94451857-94668227:+ | 4 | 7.5 |
laeverin | ENSG00000172901 | LVRN | chr5:115962454-116027619:+ | 5 | 6 |
small ArfGAP 1 | ENSG00000112305 | SMAP1 | chr6:70667776-70862015:+ | 4 | 7 |
RAS p21 protein activator 4B | ENSG00000170667 | RASA4B | chr7:102482445-102517781:- | 5 | 5.5 |
chondroitin polymerizing factor 2 | ENSG00000033100 | CHPF2 | chr7:151232489-151238827:+ | 4 | 5.5 |
stomatin like 2 | ENSG00000165283 | STOML2 | chr9:35099776-35103195:- | 4 | 10.5 |
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