GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
protocadherin gamma subfamily C, 5ENSG00000240764PCDHGC5chr5:141489121-141512979:+1213.5
unc-5 netrin receptor AENSG00000113763UNC5Achr5:176810477-176880895:+1112.5
major histocompatibility complex, class I, AENSG00000206503HLA-Achr6:29941260-29945884:+1118.5
major histocompatibility complex, class I, CENSG00000204525HLA-Cchr6:31268749-31357158:-1117.5
solute carrier family 29 member 1 (Augustine blood group)ENSG00000112759SLC29A1chr6:44219505-44234151:+1217.5
trophoblast glycoproteinENSG00000146242TPBGchr6:82363206-82370828:+1118.5
paired immunoglobin like type 2 receptor alphaENSG00000085514PILRAchr7:100367530-100400099:+1113.5
protein tyrosine phosphatase receptor type Z1ENSG00000106278PTPRZ1chr7:121873089-122062036:+1113.5
plexin A4ENSG00000221866PLXNA4chr7:132123332-132648688:-1215.5
C-type lectin domain containing 5AENSG00000258227CLEC5Achr7:141927357-141947007:-1213.5
LDL receptor related protein 12ENSG00000147650LRP12chr8:104489231-104589024:-1113.5
receptor tyrosine kinase like orphan receptor 2ENSG00000169071ROR2chr9:91563091-91950162:-1215.5
endoglinENSG00000106991ENGchr9:127815012-127854756:-1118.5
notch receptor 1ENSG00000148400NOTCH1chr9:136494444-136545862:-1119
cytochrome b-245 beta chainENSG00000165168CYBBchrX:37780011-37813461:+1217.5
interleukin 2 receptor subunit gammaENSG00000147168IL2RGchrX:71107404-71112108:-1215.5
family with sequence similarity 171 member A1ENSG00000148468FAM171A1chr10:15211643-15371062:-1117.5
tetraspanin 4ENSG00000214063TSPAN4chr11:842808-867116:+1216.5
dachsous cadherin-related 1ENSG00000166341DCHS1chr11:6621323-6655854:-1113.5
selectin P ligandENSG00000110876SELPLGchr12:108622277-108633959:-1113.5

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