GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
protocadherin gamma subfamily C, 5 | ENSG00000240764 | PCDHGC5 | chr5:141489121-141512979:+ | 12 | 13.5 |
unc-5 netrin receptor A | ENSG00000113763 | UNC5A | chr5:176810477-176880895:+ | 11 | 12.5 |
major histocompatibility complex, class I, A | ENSG00000206503 | HLA-A | chr6:29941260-29945884:+ | 11 | 18.5 |
major histocompatibility complex, class I, C | ENSG00000204525 | HLA-C | chr6:31268749-31357158:- | 11 | 17.5 |
solute carrier family 29 member 1 (Augustine blood group) | ENSG00000112759 | SLC29A1 | chr6:44219505-44234151:+ | 12 | 17.5 |
trophoblast glycoprotein | ENSG00000146242 | TPBG | chr6:82363206-82370828:+ | 11 | 18.5 |
paired immunoglobin like type 2 receptor alpha | ENSG00000085514 | PILRA | chr7:100367530-100400099:+ | 11 | 13.5 |
protein tyrosine phosphatase receptor type Z1 | ENSG00000106278 | PTPRZ1 | chr7:121873089-122062036:+ | 11 | 13.5 |
plexin A4 | ENSG00000221866 | PLXNA4 | chr7:132123332-132648688:- | 12 | 15.5 |
C-type lectin domain containing 5A | ENSG00000258227 | CLEC5A | chr7:141927357-141947007:- | 12 | 13.5 |
LDL receptor related protein 12 | ENSG00000147650 | LRP12 | chr8:104489231-104589024:- | 11 | 13.5 |
receptor tyrosine kinase like orphan receptor 2 | ENSG00000169071 | ROR2 | chr9:91563091-91950162:- | 12 | 15.5 |
endoglin | ENSG00000106991 | ENG | chr9:127815012-127854756:- | 11 | 18.5 |
notch receptor 1 | ENSG00000148400 | NOTCH1 | chr9:136494444-136545862:- | 11 | 19 |
cytochrome b-245 beta chain | ENSG00000165168 | CYBB | chrX:37780011-37813461:+ | 12 | 17.5 |
interleukin 2 receptor subunit gamma | ENSG00000147168 | IL2RG | chrX:71107404-71112108:- | 12 | 15.5 |
family with sequence similarity 171 member A1 | ENSG00000148468 | FAM171A1 | chr10:15211643-15371062:- | 11 | 17.5 |
tetraspanin 4 | ENSG00000214063 | TSPAN4 | chr11:842808-867116:+ | 12 | 16.5 |
dachsous cadherin-related 1 | ENSG00000166341 | DCHS1 | chr11:6621323-6655854:- | 11 | 13.5 |
selectin P ligand | ENSG00000110876 | SELPLG | chr12:108622277-108633959:- | 11 | 13.5 |
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