GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
transmembrane protein 156ENSG00000121895TMEM156chr4:38966744-39032922:-47.5
calcium/calmodulin dependent protein kinase II deltaENSG00000145349CAMK2Dchr4:113451032-113761927:-511
transmembrane protein 184CENSG00000164168TMEM184Cchr4:147617383-147672044:+46.5
transmembrane protein 144ENSG00000164124TMEM144chr4:158201604-158255411:+45.5
LHFPL tetraspan subfamily member 2ENSG00000145685LHFPL2chr5:78485215-78770021:-47.5
calcium/calmodulin dependent protein kinase II alphaENSG00000070808CAMK2Achr5:150219491-150290291:-57
calcium homeostasis modulator family member 4ENSG00000164451FAM26Dchr6:116529013-116558868:+56.5
solute carrier family 18 member B1ENSG00000146409SLC18B1chr6:132769370-132798553:-46.5
zinc finger DHHC-type palmitoyltransferase 4ENSG00000136247ZDHHC4chr7:6577434-6589374:+56.5
solute carrier family 35 member G5ENSG00000177710SLC35G5chr8:11330888-11332208:+45.5
transmembrane protein 64ENSG00000180694TMEM64chr8:90621995-90791632:-45.5
transient receptor potential cation channel subfamily M member 3ENSG00000083067TRPM3chr9:70529063-71446904:-45.5
mitoguardin 2ENSG00000148343FAM73Bchr9:129036621-129072082:+45.5
protein O-mannosyltransferase 1ENSG00000130714POMT1chr9:131502902-131523806:+46.5
leucine rich repeat containing 53ENSG00000162621LRRC53chr1:74469878-74512614:-45
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3ENSG00000184005ST6GALNAC3chr1:76074719-76634601:+45
pecanex 3ENSG00000197136PCNXL3chr11:65615773-65637439:+46.5
TBC1 domain family member 30ENSG00000111490TBC1D30chr12:64781193-64881032:+44.5
protein kinase C etaENSG00000027075PRKCHchr14:61187559-61550976:+45.5
SPG11 vesicle trafficking associated, spatacsinENSG00000104133SPG11chr15:44562696-44663678:-46.5

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