GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
transmembrane protein 156 | ENSG00000121895 | TMEM156 | chr4:38966744-39032922:- | 4 | 7.5 |
calcium/calmodulin dependent protein kinase II delta | ENSG00000145349 | CAMK2D | chr4:113451032-113761927:- | 5 | 11 |
transmembrane protein 184C | ENSG00000164168 | TMEM184C | chr4:147617383-147672044:+ | 4 | 6.5 |
transmembrane protein 144 | ENSG00000164124 | TMEM144 | chr4:158201604-158255411:+ | 4 | 5.5 |
LHFPL tetraspan subfamily member 2 | ENSG00000145685 | LHFPL2 | chr5:78485215-78770021:- | 4 | 7.5 |
calcium/calmodulin dependent protein kinase II alpha | ENSG00000070808 | CAMK2A | chr5:150219491-150290291:- | 5 | 7 |
calcium homeostasis modulator family member 4 | ENSG00000164451 | FAM26D | chr6:116529013-116558868:+ | 5 | 6.5 |
solute carrier family 18 member B1 | ENSG00000146409 | SLC18B1 | chr6:132769370-132798553:- | 4 | 6.5 |
zinc finger DHHC-type palmitoyltransferase 4 | ENSG00000136247 | ZDHHC4 | chr7:6577434-6589374:+ | 5 | 6.5 |
solute carrier family 35 member G5 | ENSG00000177710 | SLC35G5 | chr8:11330888-11332208:+ | 4 | 5.5 |
transmembrane protein 64 | ENSG00000180694 | TMEM64 | chr8:90621995-90791632:- | 4 | 5.5 |
transient receptor potential cation channel subfamily M member 3 | ENSG00000083067 | TRPM3 | chr9:70529063-71446904:- | 4 | 5.5 |
mitoguardin 2 | ENSG00000148343 | FAM73B | chr9:129036621-129072082:+ | 4 | 5.5 |
protein O-mannosyltransferase 1 | ENSG00000130714 | POMT1 | chr9:131502902-131523806:+ | 4 | 6.5 |
leucine rich repeat containing 53 | ENSG00000162621 | LRRC53 | chr1:74469878-74512614:- | 4 | 5 |
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | ENSG00000184005 | ST6GALNAC3 | chr1:76074719-76634601:+ | 4 | 5 |
pecanex 3 | ENSG00000197136 | PCNXL3 | chr11:65615773-65637439:+ | 4 | 6.5 |
TBC1 domain family member 30 | ENSG00000111490 | TBC1D30 | chr12:64781193-64881032:+ | 4 | 4.5 |
protein kinase C eta | ENSG00000027075 | PRKCH | chr14:61187559-61550976:+ | 4 | 5.5 |
SPG11 vesicle trafficking associated, spatacsin | ENSG00000104133 | SPG11 | chr15:44562696-44663678:- | 4 | 6.5 |
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