GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
pecanex 4ENSG00000126773PCNXL4chr14:60091911-60169133:+45.5
protein O-mannosyltransferase 2ENSG00000009830POMT2chr14:77274956-77320884:-56.5
transmembrane 6 superfamily member 1ENSG00000136404TM6SF1chr15:83107407-83144854:+45.5
mesothelin likeENSG00000162006MSLNLchr16:769428-783370:-44.5
BRICHOS domain containing 5ENSG00000182685BRICD5chr16:2209253-2211950:-45.5
NODAL modulator 3ENSG00000103226NOMO3chr16:16232495-16294814:+511
chromosome 17 open reading frame 78ENSG00000278505C17orf78chr17:37375986-37392708:+45.5
ATP binding cassette subfamily A member 10ENSG00000154263ABCA10chr17:69147214-69244846:-45.5
ATPase phospholipid transporting 8B3ENSG00000130270ATP8B3chr19:1782075-1812276:-56.5
potassium two pore domain channel subfamily K member 12ENSG00000184261KCNK12chr2:47516581-47570939:-56.5
gamma-glutamyl carboxylaseENSG00000115486GGCXchr2:85544723-85561547:-47.5
STEAP3 metalloreductaseENSG00000115107STEAP3chr2:119223831-119265652:+510.5
ceramide synthase 6ENSG00000172292CERS6chr2:168455862-168775137:+56.5
phosphatidylinositol 4-kinase alphaENSG00000241973PI4KAchr22:20707691-20859417:-59
transmembrane protein 184BENSG00000198792TMEM184Bchr22:38219291-38273034:-46.5
polycystin family receptor for egg jellyENSG00000130943PKDREJchr22:46255663-46263355:-46.5
inositol 1,4,5-trisphosphate receptor type 1ENSG00000150995ITPR1chr3:4493348-4847840:+510.5
cellular inhibitor of PP2AENSG00000163507KIAA1524chr3:108549869-108589644:-411
solute carrier family 9 member A9ENSG00000181804SLC9A9chr3:143265222-143848531:-59.5
major facilitator superfamily domain containing 1ENSG00000118855MFSD1chr3:158732198-158829719:+49.5

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