GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
pecanex 4 | ENSG00000126773 | PCNXL4 | chr14:60091911-60169133:+ | 4 | 5.5 |
protein O-mannosyltransferase 2 | ENSG00000009830 | POMT2 | chr14:77274956-77320884:- | 5 | 6.5 |
transmembrane 6 superfamily member 1 | ENSG00000136404 | TM6SF1 | chr15:83107407-83144854:+ | 4 | 5.5 |
mesothelin like | ENSG00000162006 | MSLNL | chr16:769428-783370:- | 4 | 4.5 |
BRICHOS domain containing 5 | ENSG00000182685 | BRICD5 | chr16:2209253-2211950:- | 4 | 5.5 |
NODAL modulator 3 | ENSG00000103226 | NOMO3 | chr16:16232495-16294814:+ | 5 | 11 |
chromosome 17 open reading frame 78 | ENSG00000278505 | C17orf78 | chr17:37375986-37392708:+ | 4 | 5.5 |
ATP binding cassette subfamily A member 10 | ENSG00000154263 | ABCA10 | chr17:69147214-69244846:- | 4 | 5.5 |
ATPase phospholipid transporting 8B3 | ENSG00000130270 | ATP8B3 | chr19:1782075-1812276:- | 5 | 6.5 |
potassium two pore domain channel subfamily K member 12 | ENSG00000184261 | KCNK12 | chr2:47516581-47570939:- | 5 | 6.5 |
gamma-glutamyl carboxylase | ENSG00000115486 | GGCX | chr2:85544723-85561547:- | 4 | 7.5 |
STEAP3 metalloreductase | ENSG00000115107 | STEAP3 | chr2:119223831-119265652:+ | 5 | 10.5 |
ceramide synthase 6 | ENSG00000172292 | CERS6 | chr2:168455862-168775137:+ | 5 | 6.5 |
phosphatidylinositol 4-kinase alpha | ENSG00000241973 | PI4KA | chr22:20707691-20859417:- | 5 | 9 |
transmembrane protein 184B | ENSG00000198792 | TMEM184B | chr22:38219291-38273034:- | 4 | 6.5 |
polycystin family receptor for egg jelly | ENSG00000130943 | PKDREJ | chr22:46255663-46263355:- | 4 | 6.5 |
inositol 1,4,5-trisphosphate receptor type 1 | ENSG00000150995 | ITPR1 | chr3:4493348-4847840:+ | 5 | 10.5 |
cellular inhibitor of PP2A | ENSG00000163507 | KIAA1524 | chr3:108549869-108589644:- | 4 | 11 |
solute carrier family 9 member A9 | ENSG00000181804 | SLC9A9 | chr3:143265222-143848531:- | 5 | 9.5 |
major facilitator superfamily domain containing 1 | ENSG00000118855 | MFSD1 | chr3:158732198-158829719:+ | 4 | 9.5 |
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