GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
protein O-mannose kinase | ENSG00000185900 | POMK | chr8:43093506-43123434:+ | 5 | 7.5 |
3'(2'), 5'-bisphosphate nucleotidase 2 | ENSG00000104331 | IMPAD1 | chr8:56957933-56993844:- | 5 | 9.5 |
WW domain containing E3 ubiquitin protein ligase 1 | ENSG00000123124 | WWP1 | chr8:86342738-86478420:+ | 4 | 6.5 |
solute carrier family 31 member 2 | ENSG00000136867 | SLC31A2 | chr9:113150942-113164137:+ | 5 | 6.5 |
astrotactin 2 | ENSG00000148219 | ASTN2 | chr9:116425225-117415070:- | 4 | 6.5 |
CD99 molecule (Xg blood group) | ENSG00000002586 | CD99 | chrX:2691179-2741309:+ | 4 | 12 |
LHFPL tetraspan subfamily member 1 | ENSG00000182508 | LHFPL1 | chrX:112630648-112680054:- | 4 | 5.5 |
solute carrier family 45 member 1 | ENSG00000162426 | SLC45A1 | chr1:8317826-8344167:+ | 4 | 5.5 |
patched 2 | ENSG00000117425 | PTCH2 | chr1:44819844-44843063:- | 5 | 6.5 |
TM2 domain containing 1 | ENSG00000162604 | TM2D1 | chr1:61681046-61725423:- | 4 | 7.5 |
DC-STAMP domain containing 2 | ENSG00000163354 | DCST2 | chr1:155018520-155033781:- | 4 | 5.5 |
hydroxysteroid 11-beta dehydrogenase 1 | ENSG00000117594 | HSD11B1 | chr1:209686178-209734950:+ | 4 | 6.5 |
patatin like phospholipase domain containing 2 | ENSG00000177666 | PNPLA2 | chr11:818902-825573:+ | 4 | 7 |
solute carrier family 22 member 24 | ENSG00000197658 | SLC22A24 | chr11:63079940-63144221:- | 4 | 5.5 |
ring finger protein 26 | ENSG00000173456 | RNF26 | chr11:119334527-119337313:+ | 4 | 7.5 |
roundabout guidance receptor 3 | ENSG00000154134 | ROBO3 | chr11:124865386-124881470:+ | 5 | 6 |
STT3 oligosaccharyltransferase complex catalytic subunit A | ENSG00000134910 | STT3A | chr11:125591712-125625215:+ | 4 | 11.5 |
ribitol xylosyltransferase 1 | ENSG00000118600 | TMEM5 | chr12:63779803-63809558:+ | 4 | 5 |
tetraspanin 19 | ENSG00000231738 | TSPAN19 | chr12:85014311-85036277:- | 5 | 6.5 |
SV2 related protein | ENSG00000166111 | SVOP | chr12:108907741-109021240:- | 4 | 5.5 |
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