GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
protein O-mannose kinaseENSG00000185900POMKchr8:43093506-43123434:+57.5
3'(2'), 5'-bisphosphate nucleotidase 2ENSG00000104331IMPAD1chr8:56957933-56993844:-59.5
WW domain containing E3 ubiquitin protein ligase 1ENSG00000123124WWP1chr8:86342738-86478420:+46.5
solute carrier family 31 member 2ENSG00000136867SLC31A2chr9:113150942-113164137:+56.5
astrotactin 2ENSG00000148219ASTN2chr9:116425225-117415070:-46.5
CD99 molecule (Xg blood group)ENSG00000002586CD99chrX:2691179-2741309:+412
LHFPL tetraspan subfamily member 1ENSG00000182508LHFPL1chrX:112630648-112680054:-45.5
solute carrier family 45 member 1ENSG00000162426SLC45A1chr1:8317826-8344167:+45.5
patched 2ENSG00000117425PTCH2chr1:44819844-44843063:-56.5
TM2 domain containing 1ENSG00000162604TM2D1chr1:61681046-61725423:-47.5
DC-STAMP domain containing 2ENSG00000163354DCST2chr1:155018520-155033781:-45.5
hydroxysteroid 11-beta dehydrogenase 1ENSG00000117594HSD11B1chr1:209686178-209734950:+46.5
patatin like phospholipase domain containing 2ENSG00000177666PNPLA2chr11:818902-825573:+47
solute carrier family 22 member 24ENSG00000197658SLC22A24chr11:63079940-63144221:-45.5
ring finger protein 26ENSG00000173456RNF26chr11:119334527-119337313:+47.5
roundabout guidance receptor 3ENSG00000154134ROBO3chr11:124865386-124881470:+56
STT3 oligosaccharyltransferase complex catalytic subunit AENSG00000134910STT3Achr11:125591712-125625215:+411.5
ribitol xylosyltransferase 1ENSG00000118600TMEM5chr12:63779803-63809558:+45
tetraspanin 19ENSG00000231738TSPAN19chr12:85014311-85036277:-56.5
SV2 related proteinENSG00000166111SVOPchr12:108907741-109021240:-45.5

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