GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
NIPA like domain containing 1ENSG00000163293NIPAL1chr4:47914142-48040173:+45.5
cysteine rich hydrophobic domain 2ENSG00000109220CHIC2chr4:54009789-54064690:-46.5
transmembrane serine protease 11AENSG00000187054TMPRSS11Achr4:67909385-67964140:-45.5
solute carrier family 7 member 11ENSG00000151012SLC7A11chr4:138164097-138242349:-47.5
zinc finger DHHC-type containing 11BENSG00000206077ZDHHC11Bchr5:710360-766952:-56.5
zinc finger DHHC-type containing 11ENSG00000188818ZDHHC11chr5:795606-850986:-56.5
transmembrane protein 171ENSG00000157111TMEM171chr5:73120292-73131817:+45.5
synaptic vesicle glycoprotein 2CENSG00000122012SV2Cchr5:76083172-76353939:+56.5
solute carrier family 36 member 3ENSG00000186334SLC36A3chr5:151276762-151303766:-45.5
NIPA like domain containing 4ENSG00000172548NIPAL4chr5:157460019-157474717:+45.5
tetraspanin 17ENSG00000048140TSPAN17chr5:176647387-176659054:+57.5
proline rich 7, synapticENSG00000131188PRR7chr5:177446445-177456286:+45.5
calcium homeostasis modulator family member 5ENSG00000178033FAM26Echr6:116511646-116524792:+56.5
uronyl 2-sulfotransferaseENSG00000111962USTchr6:148747328-149076990:+46.5
transmembrane p24 trafficking protein 4ENSG00000158604TMED4chr7:44577894-44582287:-510.5
ATP binding cassette subfamily A member 13ENSG00000179869ABCA13chr7:48171458-48647496:+45.5
mucin 3A, cell surface associatedENSG00000169894MUC3Achr7:100949555-100968346:+45.5
SVOP likeENSG00000157703SVOPLchr7:138594285-138701352:-45.5
limb development membrane protein 1ENSG00000105983LMBR1chr7:156668946-156893230:-46.5
solute carrier family 18 member A1ENSG00000036565SLC18A1chr8:20144855-20183206:-56.5

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