GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
membrane spanning 4-domains A15ENSG00000166961MS4A15chr11:60756953-60776732:+45.5
unc-93 homolog B1, TLR signaling regulatorENSG00000110057UNC93B1chr11:67991104-68004982:-59.5
transmembrane protein 225ENSG00000204300TMEM225chr11:123882926-123885642:-45.5
solute carrier family 15 member 5ENSG00000188991SLC15A5chr12:16188485-16277685:-45.5
tetraspanin 11ENSG00000110900TSPAN11chr12:30926428-30996599:+56.5
potassium voltage-gated channel subfamily H member 3ENSG00000135519KCNH3chr12:49539157-49558308:+56.5
myelin regulatory factor likeENSG00000166268MYRFLchr12:69825304-69959097:+45.5
solute carrier family 17 member 8ENSG00000179520SLC17A8chr12:100357079-100422059:+56.5
cytoskeleton associated protein 4ENSG00000136026CKAP4chr12:106237877-106304279:-411
ATP binding cassette subfamily B member 9ENSG00000150967ABCB9chr12:122920951-122981649:-47.5
ATPase H+/K+ transporting non-gastric alpha2 subunitENSG00000075673ATP12Achr13:24680411-24712493:+47.5
chondromodulinENSG00000136110LECT1chr13:52703264-52739812:-45.5
transmembrane protein 255BENSG00000184497TMEM255Bchr13:113759240-113816995:+45.5
solute carrier family 39 member 9ENSG00000029364SLC39A9chr14:69398015-69462388:+46.5
transmembrane protein 63CENSG00000165548TMEM63Cchr14:77116568-77259495:+56.5
InaF motif containing 2ENSG00000259330INAFM2chr15:40325216-40326715:+45.5
transmembrane protein 266ENSG00000169758C15orf27chr15:76059837-76229121:+45.5
multiple C2 and transmembrane domain containing 2ENSG00000140563MCTP2chr15:94231538-94483952:+58.5
golgi glycoprotein 1ENSG00000090863GLG1chr16:74447427-74607144:-411.5
hydroxysteroid 17-beta dehydrogenase 2ENSG00000086696HSD17B2chr16:82035004-82098534:+45.5

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