GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
ectonucleotide pyrophosphatase/phosphodiesterase family member 5ENSG00000112796ENPP5chr6:46159187-46170971:-45.5
potassium voltage-gated channel subfamily Q member 5ENSG00000185760KCNQ5chr6:72621792-73198851:+57.5
interleukin 20 receptor subunit alphaENSG00000016402IL20RAchr6:136999971-137045180:-56.5
syntaxin 1AENSG00000106089STX1Achr7:73699206-73719672:-56.5
leucine rich repeat neuronal 3ENSG00000173114LRRN3chr7:111091006-111125454:+45.5
leucine rich single-pass membrane protein 1ENSG00000181016LSMEM1chr7:112480853-112491062:+45.5
taste 2 receptor member 40ENSG00000221937TAS2R40chr7:143222037-143223079:+46
CUB and Sushi multiple domains 1ENSG00000183117CSMD1chr8:2935353-4994972:-46
TNF receptor superfamily member 10aENSG00000104689TNFRSF10Achr8:23190452-23225126:-510.5
ADAM metallopeptidase domain 7ENSG00000069206ADAM7chr8:24440930-24526970:+45.5
potassium calcium-activated channel subfamily U member 1ENSG00000215262KCNU1chr8:36784324-36936128:+57.5
ADAM metallopeptidase domain 32ENSG00000197140ADAM32chr8:39106990-39284911:+45.5
NIPA like domain containing 2ENSG00000104361NIPAL2chr8:98189833-98294393:-45.5
potassium voltage-gated channel subfamily Q member 3ENSG00000184156KCNQ3chr8:132120859-132480953:-56.5
lymphocyte antigen 6 family member DENSG00000167656LY6Dchr8:142784880-142786592:-45.5
leucine rich repeat containing 19ENSG00000184434LRRC19chr9:26993136-27005693:-45.5
equatorinENSG00000120160EQTNchr9:27284659-27297139:-56.5
contactin associated protein family member 3BENSG00000154529CNTNAP3Bchr9:41890314-42129510:-45.5
MAM domain containing 4ENSG00000177943MAMDC4chr9:136850943-136860799:+45.5
proline rich and Gla domain 1ENSG00000130962PRRG1chrX:37349275-37457295:+45.5

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