GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
cadherin related family member 4ENSG00000187492CDHR4chr3:49790732-49799835:-56.5
roundabout guidance receptor 2ENSG00000185008ROBO2chr3:75906695-77649964:+46.5
EPH receptor A6ENSG00000080224EPHA6chr3:96814581-97752460:+56.5
zona pellucida like domain containing 1ENSG00000170044ZPLD1chr3:102099244-102479841:+45.5
semaphorin 5BENSG00000082684SEMA5Bchr3:122909193-123028605:-45.5
interleukin 20 receptor subunit betaENSG00000174564IL20RBchr3:136946230-137011085:+56.5
solute carrier family 49 member 3ENSG00000169026MFSD7chr4:681829-689441:-45.5
otopetrin 1ENSG00000163982OTOP1chr4:4188803-4226889:-45.5
ATPase phospholipid transporting 8A1ENSG00000124406ATP8A1chr4:42408373-42657105:-59.5
ATPase phospholipid transporting 10D (putative)ENSG00000145246ATP10Dchr4:47485288-47593486:+57.5
leucine rich repeat, Ig-like and transmembrane domains 3ENSG00000183423LRIT3chr4:109848202-109872315:+45.5
UDP glycosyltransferase 8ENSG00000174607UGT8chr4:114598455-114678224:+45.5
ring finger protein 150ENSG00000170153RNF150chr4:140859807-141212877:-45.5
membrane associated ring-CH-type finger 1ENSG00000145416MARCH1chr4:163524298-164384050:-45.5
T cell immunoglobulin and mucin domain containing 4ENSG00000145850TIMD4chr5:156919282-156963255:-45.5
fibronectin type III domain containing 9ENSG00000172568FNDC9chr5:157341600-157345721:-45.5
butyrophilin like 3ENSG00000168903BTNL3chr5:180988845-181006727:+56.5
butyrophilin like 9ENSG00000165810BTNL9chr5:181040225-181061523:+56.5
butyrophilin subfamily 2 member A2ENSG00000124508BTN2A2chr6:26383096-26394874:+57.5
delta like non-canonical Notch ligand 2ENSG00000171462DLK2chr6:43450352-43456632:-46.5

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