GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
fibronectin type III domain containing 4 | ENSG00000115226 | FNDC4 | chr2:27491883-27495245:- | 5 | 6.5 |
aprataxin and PNKP like factor | ENSG00000169621 | APLF | chr2:68467561-68655862:+ | 4 | 5.5 |
eva-1 homolog A, regulator of programmed cell death | ENSG00000115363 | EVA1A | chr2:75469302-75569722:- | 4 | 7.5 |
transmembrane protein 127 | ENSG00000135956 | TMEM127 | chr2:96248516-96265994:- | 4 | 6.5 |
solute carrier family 9 member A2 | ENSG00000115616 | SLC9A2 | chr2:102619707-102711318:+ | 5 | 6.5 |
contactin associated protein family member 5 | ENSG00000155052 | CNTNAP5 | chr2:124025287-124915287:+ | 4 | 5.5 |
thrombospondin type 1 domain containing 7B | ENSG00000144229 | THSD7B | chr2:136765545-137677717:+ | 5 | 6.5 |
reprimo, TP53 dependent G2 arrest mediator homolog | ENSG00000177519 | RPRM | chr2:153477338-153478808:- | 4 | 5.5 |
solute carrier family 38 member 11 | ENSG00000169507 | SLC38A11 | chr2:164896186-164955525:- | 4 | 5.5 |
sodium voltage-gated channel alpha subunit 1 | ENSG00000144285 | SCN1A | chr2:165989160-166128047:- | 5 | 6.5 |
family with sequence similarity 171 member B | ENSG00000144369 | FAM171B | chr2:186693971-186765965:+ | 4 | 5.5 |
signal regulatory protein beta 2 | ENSG00000196209 | SIRPB2 | chr20:1470741-1491587:- | 5 | 6.5 |
solute carrier family 24 member 3 | ENSG00000185052 | SLC24A3 | chr20:19212646-19722937:+ | 5 | 6.5 |
transmembrane 9 superfamily member 4 | ENSG00000101337 | TM9SF4 | chr20:32109506-32167258:+ | 4 | 12.5 |
solute carrier family 32 member 1 | ENSG00000101438 | SLC32A1 | chr20:38724462-38729372:+ | 5 | 6.5 |
solute carrier family 2 member 10 | ENSG00000197496 | SLC2A10 | chr20:46709487-46736347:+ | 5 | 7.5 |
potassium voltage-gated channel subfamily B member 1 | ENSG00000158445 | KCNB1 | chr20:49363877-49482647:- | 5 | 6.5 |
potassium voltage-gated channel subfamily Q member 2 | ENSG00000075043 | KCNQ2 | chr20:63400210-63472677:- | 5 | 6.5 |
transmembrane serine protease 15 | ENSG00000154646 | TMPRSS15 | chr21:18269116-18485879:- | 4 | 5.5 |
shisa like 1 | ENSG00000138944 | KIAA1644 | chr22:44243667-44312851:- | 4 | 5.5 |
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