GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
fibronectin type III domain containing 4ENSG00000115226FNDC4chr2:27491883-27495245:-56.5
aprataxin and PNKP like factorENSG00000169621APLFchr2:68467561-68655862:+45.5
eva-1 homolog A, regulator of programmed cell deathENSG00000115363EVA1Achr2:75469302-75569722:-47.5
transmembrane protein 127ENSG00000135956TMEM127chr2:96248516-96265994:-46.5
solute carrier family 9 member A2ENSG00000115616SLC9A2chr2:102619707-102711318:+56.5
contactin associated protein family member 5ENSG00000155052CNTNAP5chr2:124025287-124915287:+45.5
thrombospondin type 1 domain containing 7BENSG00000144229THSD7Bchr2:136765545-137677717:+56.5
reprimo, TP53 dependent G2 arrest mediator homologENSG00000177519RPRMchr2:153477338-153478808:-45.5
solute carrier family 38 member 11ENSG00000169507SLC38A11chr2:164896186-164955525:-45.5
sodium voltage-gated channel alpha subunit 1ENSG00000144285SCN1Achr2:165989160-166128047:-56.5
family with sequence similarity 171 member BENSG00000144369FAM171Bchr2:186693971-186765965:+45.5
signal regulatory protein beta 2ENSG00000196209SIRPB2chr20:1470741-1491587:-56.5
solute carrier family 24 member 3ENSG00000185052SLC24A3chr20:19212646-19722937:+56.5
transmembrane 9 superfamily member 4ENSG00000101337TM9SF4chr20:32109506-32167258:+412.5
solute carrier family 32 member 1ENSG00000101438SLC32A1chr20:38724462-38729372:+56.5
solute carrier family 2 member 10ENSG00000197496SLC2A10chr20:46709487-46736347:+57.5
potassium voltage-gated channel subfamily B member 1ENSG00000158445KCNB1chr20:49363877-49482647:-56.5
potassium voltage-gated channel subfamily Q member 2ENSG00000075043KCNQ2chr20:63400210-63472677:-56.5
transmembrane serine protease 15ENSG00000154646TMPRSS15chr21:18269116-18485879:-45.5
shisa like 1ENSG00000138944KIAA1644chr22:44243667-44312851:-45.5

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