GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
leucine rich repeat containing 37 member A3ENSG00000176809LRRC37A3chr17:64854312-64919480:-45.5
potassium inwardly rectifying channel subfamily J member 16ENSG00000153822KCNJ16chr17:70053429-70135608:+45.5
solute carrier family 26 member 11ENSG00000181045SLC26A11chr17:80219699-80253500:+57.5
erythrocyte membrane protein band 4.1 like 3ENSG00000082397EPB41L3chr18:5392381-5630700:-59
VAMP associated protein AENSG00000101558VAPAchr18:9914002-9960021:+411.5
sialic acid binding Ig like lectin 15ENSG00000197046SIGLEC15chr18:45825512-45844080:+45.5
hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2ENSG00000099822HCN2chr19:589893-617159:+45.5
leucine rich repeat and Ig domain containing 3ENSG00000220008LINGO3chr19:2289784-2292024:-45.5
major facilitator superfamily domain containing 12ENSG00000161091MFSD12chr19:3538261-3574290:-57
CD209 moleculeENSG00000090659CD209chr19:7739994-7747564:-46
LDL receptor related protein 3ENSG00000130881LRP3chr19:33177603-33208867:+45.5
FXYD domain containing ion transport regulator 5ENSG00000089327FXYD5chr19:35154730-35169883:+45.5
family with sequence similarity 187 member BENSG00000177558FAM187Bchr19:35224800-35228729:-45.5
delta like canonical Notch ligand 3ENSG00000090932DLL3chr19:39498895-39508481:+46.5
CEA cell adhesion molecule 3ENSG00000170956CEACAM3chr19:41796437-41811553:+45.5
transmembrane protein 145ENSG00000167619TMEM145chr19:42313325-42325062:+45.5
CEA cell adhesion molecule 19ENSG00000186567CEACAM19chr19:44662278-44684359:+45.5
acid phosphatase 4ENSG00000142513ACPTchr19:50790415-50795224:+45.5
V-set and immunoglobulin domain containing 10 likeENSG00000186806VSIG10Lchr19:51331536-51342124:-45.5
chromosome 19 open reading frame 18ENSG00000177025C19orf18chr19:57958437-57974534:-45.5

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