GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
sushi domain containing 6ENSG00000100647SUSD6chr14:69611596-69715142:+46.5
ADAM metallopeptidase domain 21ENSG00000139985ADAM21chr14:70452157-70459899:+45.5
ADAM metallopeptidase domain 20ENSG00000134007ADAM20chr14:70522358-70535015:-45.5
dual oxidase maturation factor 1ENSG00000140254DUOXA1chr15:45117367-45129938:-45.5
immunoglobulin superfamily DCC subclass member 3ENSG00000174498IGDCC3chr15:65327127-65378040:-45.5
secretory carrier membrane protein 5ENSG00000198794SCAMP5chr15:74957219-75021496:+56.5
kringle containing transmembrane protein 2ENSG00000131650KREMEN2chr16:2963944-2968383:+45.5
modulator of smoothenedENSG00000185716C16orf52chr16:22007638-22087534:+45.5
solute carrier family 5 member 11ENSG00000158865SLC5A11chr16:24845841-24911628:+56.5
GSG1 likeENSG00000169181GSG1Lchr16:27787535-28063509:-56.5
solute carrier family 12 member 4ENSG00000124067SLC12A4chr16:67943474-67969601:-46.5
cytochrome b-245 alpha chainENSG00000051523CYBAchr16:88643283-88651152:-59.5
TLC domain containing 3AENSG00000167695FAM57Achr17:732412-742972:+45.5
sphingolipid transporter 3 (putative)ENSG00000182557SPNS3chr17:4433688-4488208:+46
solute carrier family 16 member 11ENSG00000174326SLC16A11chr17:7041630-7043923:-45.5
peripheral myelin protein 22ENSG00000109099PMP22chr17:15229777-15265326:-56.5
transmembrane protein 97ENSG00000109084TMEM97chr17:28319095-28328685:+57.5
transmembrane protein 106AENSG00000184988TMEM106Achr17:43211835-43220041:+46.5
leucine rich repeat containing 37AENSG00000176681LRRC37Achr17:46292733-46337794:+45.5
leucine rich repeat containing 37 member A2ENSG00000238083LRRC37A2chr17:46511511-46555650:+45.5

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