GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
chromosome 11 open reading frame 87 | ENSG00000185742 | C11orf87 | chr11:109422120-109429114:+ | 4 | 6.5 |
myelin protein zero like 3 | ENSG00000160588 | MPZL3 | chr11:118226690-118252350:- | 4 | 5.5 |
ATP binding cassette subfamily G member 4 | ENSG00000172350 | ABCG4 | chr11:119149012-119162653:+ | 4 | 5.5 |
serine/threonine/tyrosine kinase 1 | ENSG00000060140 | STYK1 | chr12:10618939-10674318:- | 4 | 5.5 |
taste 2 receptor member 50 | ENSG00000212126 | TAS2R50 | chr12:10985913-10986912:- | 4 | 6 |
taste 2 receptor member 31 | ENSG00000256436 | TAS2R31 | chr12:11030387-11031407:- | 4 | 6 |
MANSC domain containing 4 | ENSG00000205693 | MANSC4 | chr12:27762738-27771276:- | 4 | 5.5 |
transmembrane protein 117 | ENSG00000139173 | TMEM117 | chr12:43835967-44389762:+ | 4 | 5.5 |
biorientation of chromosomes in cell division 1 like 2 | ENSG00000197376 | OR8S1 | chr12:48507354-48529897:+ | 4 | 5.5 |
solute carrier family 4 member 8 | ENSG00000050438 | SLC4A8 | chr12:51391317-51515763:+ | 4 | 5.5 |
anti-Mullerian hormone receptor type 2 | ENSG00000135409 | AMHR2 | chr12:53423855-53431534:+ | 5 | 6.5 |
bestrophin 3 | ENSG00000127325 | BEST3 | chr12:69643360-69699476:- | 4 | 5.5 |
transmembrane protein 132B | ENSG00000139364 | TMEM132B | chr12:125186836-125662377:+ | 4 | 5.5 |
transmembrane protein 132C | ENSG00000181234 | TMEM132C | chr12:128267403-128707915:+ | 4 | 7.5 |
TNF receptor superfamily member 19 | ENSG00000127863 | TNFRSF19 | chr13:23570370-23676104:+ | 5 | 7.5 |
transient receptor potential cation channel subfamily C member 4 | ENSG00000133107 | TRPC4 | chr13:37636636-37870425:- | 5 | 7.5 |
SLIT and NTRK like family member 1 | ENSG00000178235 | SLITRK1 | chr13:83877205-83882393:- | 5 | 6.5 |
G protein-coupled receptor 180 | ENSG00000152749 | GPR180 | chr13:94601903-94634645:+ | 4 | 8.5 |
leucine rich repeat and fibronectin type III domain containing 5 | ENSG00000165379 | LRFN5 | chr14:41607570-41904549:+ | 4 | 5.5 |
G protein-coupled receptor 137C | ENSG00000180998 | GPR137C | chr14:52553148-52637713:+ | 4 | 5.5 |
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