GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
chromosome 11 open reading frame 87ENSG00000185742C11orf87chr11:109422120-109429114:+46.5
myelin protein zero like 3ENSG00000160588MPZL3chr11:118226690-118252350:-45.5
ATP binding cassette subfamily G member 4ENSG00000172350ABCG4chr11:119149012-119162653:+45.5
serine/threonine/tyrosine kinase 1ENSG00000060140STYK1chr12:10618939-10674318:-45.5
taste 2 receptor member 50ENSG00000212126TAS2R50chr12:10985913-10986912:-46
taste 2 receptor member 31ENSG00000256436TAS2R31chr12:11030387-11031407:-46
MANSC domain containing 4ENSG00000205693MANSC4chr12:27762738-27771276:-45.5
transmembrane protein 117ENSG00000139173TMEM117chr12:43835967-44389762:+45.5
biorientation of chromosomes in cell division 1 like 2ENSG00000197376OR8S1chr12:48507354-48529897:+45.5
solute carrier family 4 member 8ENSG00000050438SLC4A8chr12:51391317-51515763:+45.5
anti-Mullerian hormone receptor type 2ENSG00000135409AMHR2chr12:53423855-53431534:+56.5
bestrophin 3ENSG00000127325BEST3chr12:69643360-69699476:-45.5
transmembrane protein 132BENSG00000139364TMEM132Bchr12:125186836-125662377:+45.5
transmembrane protein 132CENSG00000181234TMEM132Cchr12:128267403-128707915:+47.5
TNF receptor superfamily member 19ENSG00000127863TNFRSF19chr13:23570370-23676104:+57.5
transient receptor potential cation channel subfamily C member 4ENSG00000133107TRPC4chr13:37636636-37870425:-57.5
SLIT and NTRK like family member 1ENSG00000178235SLITRK1chr13:83877205-83882393:-56.5
G protein-coupled receptor 180ENSG00000152749GPR180chr13:94601903-94634645:+48.5
leucine rich repeat and fibronectin type III domain containing 5ENSG00000165379LRFN5chr14:41607570-41904549:+45.5
G protein-coupled receptor 137CENSG00000180998GPR137Cchr14:52553148-52637713:+45.5

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