GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
hyperpolarization activated cyclic nucleotide gated potassium channel 3ENSG00000143630HCN3chr1:155277583-155289848:+45.5
Rh family B glycoprotein (gene/pseudogene)ENSG00000132677RHBGchr1:156369212-156385219:+56.5
V-set and immunoglobulin domain containing 8ENSG00000243284VSIG8chr1:159854316-159862657:-45.5
hydroxysteroid 17-beta dehydrogenase 7ENSG00000132196HSD17B7chr1:162790702-162812817:+57
astrotactin 1ENSG00000152092ASTN1chr1:176857302-177164973:-45.5
xenotropic and polytropic retrovirus receptor 1ENSG00000143324XPR1chr1:180632004-180890251:+58.5
leucine rich repeat neuronal 2ENSG00000170382LRRN2chr1:204617170-204685733:-45.5
sushi domain containing 4ENSG00000143502SUSD4chr1:223220819-223364202:-45.5
MAM and LDL receptor class A domain containing 1ENSG00000204740MALRD1chr10:19048771-19790401:+45.5
leucine rich repeat, Ig-like and transmembrane domains 1ENSG00000148602LRIT1chr10:84231593-84241461:-45.5
tectonic family member 3ENSG00000119977TCTN3chr10:95663396-95694143:-46.5
scavenger receptor family member expressed on T cells 1ENSG00000214279SCART1chr10:133453928-133523558:+56.5
single Ig and TIR domain containingENSG00000185187SIGIRRchr11:405716-417455:-46.5
potassium voltage-gated channel subfamily Q member 1ENSG00000053918KCNQ1chr11:2444684-2849109:+56.5
macrophage expressed 1ENSG00000197629MPEG1chr11:59208510-59212951:-45.5
LRRN4 C-terminal likeENSG00000177363LRRN4CLchr11:62686402-62689899:-46.5
neurexin 2ENSG00000110076NRXN2chr11:64606174-64723188:-47.5
leucine rich repeat and fibronectin type III domain containing 4ENSG00000173621LRFN4chr11:66856647-66860475:+46.5
N-acetylated alpha-linked acidic dipeptidase 2ENSG00000077616NAALAD2chr11:90131515-90192894:+46.5
hephaestin like 1ENSG00000181333HEPHL1chr11:94021361-94113751:+56.5

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