GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
CD200 receptor 1 likeENSG00000206531CD200R1Lchr3:112815709-112846856:-57
clarin 1ENSG00000163646CLRN1chr3:150926163-150972999:-45.5
taste 2 receptor member 1ENSG00000169777TAS2R1chr5:9628997-9712378:-46
hepatitis A virus cellular receptor 1ENSG00000113249HAVCR1chr5:157029413-157059119:-46
solute carrier family 17 member 3ENSG00000124564SLC17A3chr6:25833066-25882286:-45.5
major histocompatibility complex, class II, DQ beta 1ENSG00000179344HLA-DQB1chr6:32659467-32668383:-48.5
opsin 5ENSG00000124818OPN5chr6:47781982-47832780:+57
sperm acrosome associated 1ENSG00000118434SPACA1chr6:88047789-88066832:+57
taste 2 receptor member 3ENSG00000127362TAS2R3chr7:141764097-141765197:+46
taste 2 receptor member 38ENSG00000257138TAS2R38chr7:141972631-141973773:-46
olfactory receptor family 2 subfamily A member 42ENSG00000212807OR2A42chr7:144231911-144232843:-45.5
unc-5 netrin receptor DENSG00000156687UNC5Dchr8:35235457-35796550:+45.5
beta-1,4-galactosyltransferase 1ENSG00000086062B4GALT1chr9:33104082-33167356:-49.5
Xg glycoprotein (Xg blood group)ENSG00000124343XGchrX:2752050-2815927:+45.5
fibronectin type III domain containing 10ENSG00000228594C1orf233chr1:1598012-1600096:-45.5
syndecan 3ENSG00000162512SDC3chr1:30869467-30908761:-45.5
potassium voltage-gated channel subfamily Q member 4ENSG00000117013KCNQ4chr1:40784012-40840452:+56.5
ADAM metallopeptidase domain 30ENSG00000134249ADAM30chr1:119893533-119896495:-45.5
leucine rich repeat and Ig domain containing 4ENSG00000213171LINGO4chr1:151800264-151806154:-45.5
solute carrier family 39 member 1ENSG00000143570SLC39A1chr1:153959099-153968184:-56.5

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