GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
taste 2 receptor member 8ENSG00000121314TAS2R8chr12:10806051-10807293:-46
taste 2 receptor member 9ENSG00000121381TAS2R9chr12:10809137-10810168:-46
taste 2 receptor member 19ENSG00000212124TAS2R19chr12:11021619-11022620:-46
taste 2 receptor member 30ENSG00000256188TAS2R30chr12:11077313-11134644:-46
spectrin repeat containing nuclear envelope protein 2ENSG00000054654SYNE2chr14:63852983-64226433:+47.5
transmembrane p24 trafficking protein 10ENSG00000170348TMED10chr14:75131470-75176631:-511.5
hyperpolarization activated cyclic nucleotide gated potassium channel 4ENSG00000138622HCN4chr15:73319859-73369264:-46.5
neuropilin and tolloid like 2ENSG00000171208NETO2chr16:47077703-47143997:-46
shisa family member 6ENSG00000188803SHISA6chr17:11241263-11564063:+56.5
reprimo likeENSG00000179673RPRMLchr17:46978156-46979248:-45.5
calcium voltage-gated channel subunit alpha1 GENSG00000006283CACNA1Gchr17:50561068-50627474:+56.5
carbonic anhydrase 4ENSG00000167434CA4chr17:60149936-60170899:+46.5
presenilin enhancer, gamma-secretase subunitENSG00000205155PSENENchr19:35745114-35747519:+57
CEA cell adhesion molecule 21ENSG00000007129CEACAM21chr19:41549518-41586844:+46
golgi associated olfactory signaling regulatorENSG00000261949GFYchr19:49423749-49428818:+46
shisa family member 7ENSG00000187902SHISA7chr19:55428740-55442863:-56.5
vesicle associated membrane protein 8ENSG00000118640VAMP8chr2:85561562-85582031:+410.5
eva-1 homolog CENSG00000166979EVA1Cchr21:32412006-32515397:+46
zinc and ring finger 3ENSG00000183579ZNRF3chr22:28883592-29057487:+56.5
leucine rich repeats and transmembrane domains 1ENSG00000144771LRTM1chr3:54918237-54967088:-46

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