GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
elastin microfibril interfacer 1ENSG00000138080EMILIN1chr2:27078567-27086408:+56
heat shock protein 90 alpha family class B member 1ENSG00000096384HSP90AB1chr6:44246166-44253888:+613
WD repeat domain 13ENSG00000101940WDR13chrX:48590042-48608867:+56
potassium two pore domain channel subfamily K member 1ENSG00000135750KCNK1chr1:233614004-233672512:+59.5
zinc finger DHHC-type palmitoyltransferase 20ENSG00000180776ZDHHC20chr13:21372573-21459370:-513
hyperpolarization activated cyclic nucleotide gated potassium channel 1ENSG00000164588HCN1chr5:45259247-45696151:-49.5
adiponectin receptor 1ENSG00000159346ADIPOR1chr1:202940823-202958572:-59.5
olfactory receptor family 2 subfamily T member 5ENSG00000203661OR2T5chr1:248488589-248489536:+46
retinal G protein coupled receptorENSG00000148604RGRchr10:84245053-84259960:+57
adhesion G protein-coupled receptor A1ENSG00000197177ADGRA1chr10:133070929-133131675:+46
membrane frizzled-related proteinENSG00000235718MFRPchr11:119341168-119346673:-46
G protein-coupled receptor 135ENSG00000181619GPR135chr14:59429022-59465342:-46
CD300e moleculeENSG00000186407CD300Echr17:74609887-74623738:-45.5
potassium calcium-activated channel subfamily N member 4ENSG00000104783KCNN4chr19:43766533-43781257:-59.5
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3ENSG00000242019KIR3DL3chr19:54724479-54736536:+46
natural cytotoxicity triggering receptor 1ENSG00000189430NCR1chr19:54906150-54916140:+45.5
adhesion G protein-coupled receptor F3ENSG00000173567ADGRF3chr2:26308173-26346817:-46
ATP binding cassette subfamily G member 8ENSG00000143921ABCG8chr2:43838964-43878466:+47.5
potassium voltage-gated channel subfamily E regulatory subunit 2ENSG00000159197KCNE2chr21:34364024-34371389:+57.5
olfactory receptor family 2 subfamily J member 2ENSG00000204700OR2J2chr6:29173303-29174574:+46

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