GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
myotubularin 1ENSG00000171100MTM1chrX:150568619-150673322:+57
chloride channel accessory 1ENSG00000016490CLCA1chr1:86468368-86500289:+66
ADAMTS like 4ENSG00000143382ADAMTSL4chr1:150549369-150560937:+55
otogelinENSG00000188162OTOGchr11:17547373-17647150:+55
Fas associated via death domainENSG00000168040FADDchr11:70203163-70207390:+57
keratin 1ENSG00000167768KRT1chr12:52674736-52680407:-510
T cell receptor alpha variable 19ENSG00000211799TRAV19chr14:22007512-22008181:+55
heat shock protein 90 alpha family class A member 1ENSG00000080824HSP90AA1chr14:102080738-102139699:-613
immunoglobulin heavy variable 4-34ENSG00000211956IGHV4-34chr14:106373663-106374145:-66
complement C1q binding proteinENSG00000108561C1QBPchr17:5432777-5448830:-510
STAM binding proteinENSG00000124356STAMBPchr2:73828916-73873659:+66
immunoglobulin kappa variable 5-2ENSG00000211599IGKV5-2chr2:88897232-88897784:+55
immunoglobulin kappa variable 1D-39ENSG00000251546IGKV1D-39chr2:89862482-89862981:+55
immunoglobulin lambda variable 1-51ENSG00000211644IGLV1-51chr22:22322472-22322980:+55
eukaryotic translation elongation factor 1 alpha 1ENSG00000156508EEF1A1chr6:73515750-73523797:-512
T cell receptor beta variable 12-3ENSG00000274752TRBV12-3chr7:142560423-142560931:+55
talin 1ENSG00000137076TLN1chr9:35696948-35732395:-511
cingulinENSG00000143375CGNchr1:151510510-151538692:+56
chromosome 14 open reading frame 93ENSG00000100802C14orf93chr14:22985908-23010166:-55
scavenger receptor cysteine rich family member with 5 domainsENSG00000179954SSC5Dchr19:55488404-55519098:+55

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