GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
ankyrin 2 | ENSG00000145362 | ANK2 | chr4:112818109-113383740:+ | 6 | 8 |
brain abundant membrane attached signal protein 1 | ENSG00000176788 | BASP1 | chr5:17065598-17276843:+ | 5 | 10 |
erbb2 interacting protein | ENSG00000112851 | ERBB2IP | chr5:65926475-66082549:+ | 5 | 9 |
ADAM metallopeptidase with thrombospondin type 1 motif 2 | ENSG00000087116 | ADAMTS2 | chr5:179110851-179345430:- | 5 | 6.5 |
desmoplakin | ENSG00000096696 | DSP | chr6:7541575-7586717:+ | 6 | 11 |
RAB23, member RAS oncogene family | ENSG00000112210 | RAB23 | chr6:57186992-57222314:- | 6 | 7 |
sorting nexin 9 | ENSG00000130340 | SNX9 | chr6:157700387-157945077:+ | 5 | 7 |
paraoxonase 3 | ENSG00000105852 | PON3 | chr7:95359944-95396368:- | 5 | 5.5 |
amine oxidase copper containing 1 | ENSG00000002726 | AOC1 | chr7:150824627-150861504:+ | 6 | 7 |
protein tyrosine kinase 2 beta | ENSG00000120899 | PTK2B | chr8:27311482-27459391:+ | 6 | 10 |
lymphocyte antigen 96 | ENSG00000154589 | LY96 | chr8:73991352-74029087:+ | 5 | 6 |
annexin A13 | ENSG00000104537 | ANXA13 | chr8:123680794-123737407:- | 6 | 6 |
KN motif and ankyrin repeat domains 1 | ENSG00000107104 | KANK1 | chr9:470291-746106:+ | 5 | 5 |
neuronal calcium sensor 1 | ENSG00000107130 | NCS1 | chr9:130172578-130237304:+ | 5 | 6 |
anosmin 1 | ENSG00000011201 | ANOS1 | chrX:8528874-8732187:- | 5 | 6 |
RP2 activator of ARL3 GTPase | ENSG00000102218 | RP2 | chrX:46836940-46882358:+ | 5 | 9 |
APC membrane recruitment protein 1 | ENSG00000184675 | AMER1 | chrX:64185117-64205744:- | 6 | 6 |
moesin | ENSG00000147065 | MSN | chrX:65588377-65741931:+ | 5 | 11 |
O-linked N-acetylglucosamine (GlcNAc) transferase | ENSG00000147162 | OGT | chrX:71533083-71575897:+ | 5 | 8 |
angiomotin | ENSG00000126016 | AMOT | chrX:112774503-112840815:- | 5 | 5 |
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