GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
ankyrin 2ENSG00000145362ANK2chr4:112818109-113383740:+68
brain abundant membrane attached signal protein 1ENSG00000176788BASP1chr5:17065598-17276843:+510
erbb2 interacting proteinENSG00000112851ERBB2IPchr5:65926475-66082549:+59
ADAM metallopeptidase with thrombospondin type 1 motif 2ENSG00000087116ADAMTS2chr5:179110851-179345430:-56.5
desmoplakinENSG00000096696DSPchr6:7541575-7586717:+611
RAB23, member RAS oncogene familyENSG00000112210RAB23chr6:57186992-57222314:-67
sorting nexin 9ENSG00000130340SNX9chr6:157700387-157945077:+57
paraoxonase 3ENSG00000105852PON3chr7:95359944-95396368:-55.5
amine oxidase copper containing 1ENSG00000002726AOC1chr7:150824627-150861504:+67
protein tyrosine kinase 2 betaENSG00000120899PTK2Bchr8:27311482-27459391:+610
lymphocyte antigen 96ENSG00000154589LY96chr8:73991352-74029087:+56
annexin A13ENSG00000104537ANXA13chr8:123680794-123737407:-66
KN motif and ankyrin repeat domains 1ENSG00000107104KANK1chr9:470291-746106:+55
neuronal calcium sensor 1ENSG00000107130NCS1chr9:130172578-130237304:+56
anosmin 1ENSG00000011201ANOS1chrX:8528874-8732187:-56
RP2 activator of ARL3 GTPaseENSG00000102218RP2chrX:46836940-46882358:+59
APC membrane recruitment protein 1ENSG00000184675AMER1chrX:64185117-64205744:-66
moesinENSG00000147065MSNchrX:65588377-65741931:+511
O-linked N-acetylglucosamine (GlcNAc) transferaseENSG00000147162OGTchrX:71533083-71575897:+58
angiomotinENSG00000126016AMOTchrX:112774503-112840815:-55

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