GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
C-type lectin domain family 12 member A | ENSG00000172322 | CLEC12A | chr12:9951316-9995694:+ | 11 | 15.5 |
adhesion molecule with Ig like domain 2 | ENSG00000139211 | AMIGO2 | chr12:47075707-47079951:- | 11 | 13.5 |
integrin subunit beta 7 | ENSG00000139626 | ITGB7 | chr12:53191318-53207307:- | 12 | 15.5 |
protocadherin 17 | ENSG00000118946 | PCDH17 | chr13:57631810-57729311:+ | 12 | 14.5 |
integrin subunit alpha 11 | ENSG00000137809 | ITGA11 | chr15:68296533-68432162:- | 11 | 15.5 |
neuroplastin | ENSG00000156642 | NPTN | chr15:73560014-73634134:- | 12 | 19.5 |
cadherin 5 | ENSG00000179776 | CDH5 | chr16:66366622-66404786:+ | 12 | 14.5 |
angiotensin I converting enzyme | ENSG00000159640 | ACE | chr17:63477061-63498380:+ | 12 | 16.5 |
desmocollin 2 | ENSG00000134755 | DSC2 | chr18:31058840-31102415:- | 12 | 15.5 |
TNF receptor superfamily member 11a | ENSG00000141655 | TNFRSF11A | chr18:62325287-62391292:+ | 11 | 13.5 |
signal peptide peptidase like 2B | ENSG00000005206 | SPPL2B | chr19:2328615-2354806:+ | 12 | 15.5 |
cysteine rich transmembrane BMP regulator 1 | ENSG00000150938 | CRIM1 | chr2:36355926-36551135:+ | 11 | 15.5 |
solute carrier family 5 member 7 | ENSG00000115665 | SLC5A7 | chr2:107986523-108013994:+ | 11 | 12.5 |
integrin subunit beta 6 | ENSG00000115221 | ITGB6 | chr2:160099666-160271888:- | 12 | 15.5 |
integrin subunit alpha 6 | ENSG00000091409 | ITGA6 | chr2:172427354-172506282:+ | 11 | 18.5 |
integrin subunit alpha V | ENSG00000138448 | ITGAV | chr2:186590065-186680901:+ | 11 | 19.5 |
CD28 molecule | ENSG00000178562 | CD28 | chr2:203706475-203738912:+ | 11 | 12.5 |
signal regulatory protein beta 1 | ENSG00000101307 | SIRPB1 | chr20:1563521-1620061:- | 12 | 18.5 |
attractin | ENSG00000088812 | ATRN | chr20:3471040-3651122:+ | 11 | 17.5 |
solute carrier family 23 member 2 | ENSG00000089057 | SLC23A2 | chr20:4852356-5010293:- | 11 | 12.5 |
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