GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
tight junction protein 1ENSG00000104067TJP1chr15:29699367-29968865:-610
SLC9A3 regulator 2ENSG00000065054SLC9A3R2chr16:2025356-2039026:+58
myosin ICENSG00000197879MYO1Cchr17:1464098-1492812:-612
caveolae associated protein 1ENSG00000177469PTRFchr17:42402452-42423517:-59
microtubule associated protein tauENSG00000186868MAPTchr17:45894382-46028334:+66
SLC9A3 regulator 1ENSG00000109062SLC9A3R1chr17:74748652-74769353:+58
paralemminENSG00000099864PALMchr19:708939-748329:+56
vasodilator stimulated phosphoproteinENSG00000125753VASPchr19:45506579-45526983:+58
EH domain containing 2ENSG00000024422EHD2chr19:47713343-47743134:+59
cytohesin 2ENSG00000105443CYTH2chr19:48469032-48482314:+56
EH domain containing 3ENSG00000013016EHD3chr2:31234337-31269447:+56
adducin 2ENSG00000075340ADD2chr2:70607618-70768225:-67
plakophilin 4ENSG00000144283PKP4chr2:158456964-158682879:+68
ADP ribosylation factor like GTPase 4CENSG00000188042ARL4Cchr2:234493041-234497053:-66
protein phosphatase 1 regulatory subunit 16BENSG00000101445PPP1R16Bchr20:38805705-38923024:+55
ribosomal protein SAENSG00000168028RPSAchr3:39406689-39412542:+511
catenin beta 1ENSG00000168036CTNNB1chr3:41194837-41260096:+610
growth associated protein 43ENSG00000172020GAP43chr3:115623324-115721490:+67
discs large MAGUK scaffold protein 1ENSG00000075711DLG1chr3:197042560-197299300:-610
tec protein tyrosine kinaseENSG00000135605TECchr4:48135783-48269864:-55

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