GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
organic solute carrier partner 1 | ENSG00000116885 | OSCP1 | chr1:36415827-36450451:- | 5 | 5 |
CDC42 small effector 1 | ENSG00000197622 | CDC42SE1 | chr1:151050971-151070325:- | 6 | 7 |
phosphatidylinositol-4-phosphate 5-kinase type 1 alpha | ENSG00000143398 | PIP5K1A | chr1:151197949-151249536:+ | 5 | 6 |
S100 calcium binding protein A9 | ENSG00000163220 | S100A9 | chr1:153357854-153361027:+ | 5 | 8 |
S100 calcium binding protein A6 | ENSG00000197956 | S100A6 | chr1:153534599-153536244:- | 5 | 10 |
RAB13, member RAS oncogene family | ENSG00000143545 | RAB13 | chr1:153981617-153986358:- | 6 | 10 |
intelectin 1 | ENSG00000179914 | ITLN1 | chr1:160876539-160885170:- | 5 | 5 |
adducin 3 | ENSG00000148700 | ADD3 | chr10:109996368-110135565:+ | 6 | 7 |
lymphocyte specific protein 1 | ENSG00000130592 | LSP1 | chr11:1852970-1892267:+ | 5 | 6 |
receptor associated protein of the synapse | ENSG00000165917 | RAPSN | chr11:47437757-47449178:- | 5 | 5 |
catenin delta 1 | ENSG00000198561 | CTNND1 | chr11:57753243-57819546:+ | 6 | 12 |
cobalamin binding intrinsic factor | ENSG00000134812 | GIF | chr11:59829268-59845501:- | 5 | 5 |
EH domain containing 1 | ENSG00000110047 | EHD1 | chr11:64851642-64888296:- | 5 | 11 |
cystatin E/M | ENSG00000175315 | CST6 | chr11:66011841-66013505:+ | 5 | 5.5 |
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 | ENSG00000149357 | LAMTOR1 | chr11:72085895-72103387:- | 6 | 10 |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | ENSG00000186635 | ARAP1 | chr11:72685069-72793599:- | 5 | 7 |
synaptotagmin like 2 | ENSG00000137501 | SYTL2 | chr11:85694224-85811159:- | 6 | 8 |
trichoplein keratin filament binding | ENSG00000139437 | TCHP | chr12:109900264-109983841:+ | 5 | 5 |
ras homolog family member J | ENSG00000126785 | RHOJ | chr14:63204114-63293219:+ | 6 | 7 |
membrane palmitoylated protein 5 | ENSG00000072415 | MPP5 | chr14:67241109-67335819:+ | 6 | 8 |
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