GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
organic solute carrier partner 1ENSG00000116885OSCP1chr1:36415827-36450451:-55
CDC42 small effector 1ENSG00000197622CDC42SE1chr1:151050971-151070325:-67
phosphatidylinositol-4-phosphate 5-kinase type 1 alphaENSG00000143398PIP5K1Achr1:151197949-151249536:+56
S100 calcium binding protein A9ENSG00000163220S100A9chr1:153357854-153361027:+58
S100 calcium binding protein A6ENSG00000197956S100A6chr1:153534599-153536244:-510
RAB13, member RAS oncogene familyENSG00000143545RAB13chr1:153981617-153986358:-610
intelectin 1ENSG00000179914ITLN1chr1:160876539-160885170:-55
adducin 3ENSG00000148700ADD3chr10:109996368-110135565:+67
lymphocyte specific protein 1ENSG00000130592LSP1chr11:1852970-1892267:+56
receptor associated protein of the synapseENSG00000165917RAPSNchr11:47437757-47449178:-55
catenin delta 1ENSG00000198561CTNND1chr11:57753243-57819546:+612
cobalamin binding intrinsic factorENSG00000134812GIFchr11:59829268-59845501:-55
EH domain containing 1ENSG00000110047EHD1chr11:64851642-64888296:-511
cystatin E/MENSG00000175315CST6chr11:66011841-66013505:+55.5
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1ENSG00000149357LAMTOR1chr11:72085895-72103387:-610
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1ENSG00000186635ARAP1chr11:72685069-72793599:-57
synaptotagmin like 2ENSG00000137501SYTL2chr11:85694224-85811159:-68
trichoplein keratin filament bindingENSG00000139437TCHPchr12:109900264-109983841:+55
ras homolog family member JENSG00000126785RHOJchr14:63204114-63293219:+67
membrane palmitoylated protein 5ENSG00000072415MPP5chr14:67241109-67335819:+68

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