GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
fibulin 2ENSG00000163520FBLN2chr3:13549131-13638422:+57
olfactory receptor family 5 subfamily AC member 1 (gene/pseudogene)ENSG00000213439OR5AC1chr3:98064472-98065396:+55.5
adaptor related protein complex 2 subunit mu 1ENSG00000161203AP2M1chr3:184174689-184184091:+611
lipase HENSG00000163898LIPHchr3:185506262-185552613:-55.5
adducin 1ENSG00000087274ADD1chr4:2843857-2930076:+69.5
granzyme AENSG00000145649GZMAchr5:55102648-55110252:+55
olfactory receptor family 2 subfamily W member 6 pseudogeneENSG00000168126OR2W6Pchr6:27937465-27938403:+55.5
olfactory receptor family 2 subfamily B member 8 pseudogeneENSG00000182477OR2B8Pchr6:28053228-28054165:-55.5
flotillin 1ENSG00000137312FLOT1chr6:30727709-30742733:-58.5
FYN proto-oncogene, Src family tyrosine kinaseENSG00000010810FYNchr6:111660332-111873452:-68
utrophinENSG00000152818UTRNchr6:144285701-144853034:+58
ezrinENSG00000092820EZRchr6:158765741-158819412:-511.5
plasminogenENSG00000122194PLGchr6:160702238-160753315:+58
olfactory receptor family 9 subfamily A member 1 pseudogeneENSG00000237621OR9A1Pchr7:141887148-141888092:+55.5
olfactory receptor family 2 subfamily F member 1 (gene/pseudogene)ENSG00000213215OR2F1chr7:143959927-143961015:+55.5
LYN proto-oncogene, Src family tyrosine kinaseENSG00000254087LYNchr8:55879813-56014168:+69
LY6/PLAUR domain containing 2ENSG00000197353LYPD2chr8:142750150-142752534:-55
scribble planar cell polarity proteinENSG00000180900SCRIBchr8:143790920-143815379:-610
spleen associated tyrosine kinaseENSG00000165025SYKchr9:90801787-90898549:+56
olfactory receptor family 1 subfamily B member 1 (gene/pseudogene)ENSG00000280094OR1B1chr9:122628579-122629573:-55.5

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