GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
fibulin 2 | ENSG00000163520 | FBLN2 | chr3:13549131-13638422:+ | 5 | 7 |
olfactory receptor family 5 subfamily AC member 1 (gene/pseudogene) | ENSG00000213439 | OR5AC1 | chr3:98064472-98065396:+ | 5 | 5.5 |
adaptor related protein complex 2 subunit mu 1 | ENSG00000161203 | AP2M1 | chr3:184174689-184184091:+ | 6 | 11 |
lipase H | ENSG00000163898 | LIPH | chr3:185506262-185552613:- | 5 | 5.5 |
adducin 1 | ENSG00000087274 | ADD1 | chr4:2843857-2930076:+ | 6 | 9.5 |
granzyme A | ENSG00000145649 | GZMA | chr5:55102648-55110252:+ | 5 | 5 |
olfactory receptor family 2 subfamily W member 6 pseudogene | ENSG00000168126 | OR2W6P | chr6:27937465-27938403:+ | 5 | 5.5 |
olfactory receptor family 2 subfamily B member 8 pseudogene | ENSG00000182477 | OR2B8P | chr6:28053228-28054165:- | 5 | 5.5 |
flotillin 1 | ENSG00000137312 | FLOT1 | chr6:30727709-30742733:- | 5 | 8.5 |
FYN proto-oncogene, Src family tyrosine kinase | ENSG00000010810 | FYN | chr6:111660332-111873452:- | 6 | 8 |
utrophin | ENSG00000152818 | UTRN | chr6:144285701-144853034:+ | 5 | 8 |
ezrin | ENSG00000092820 | EZR | chr6:158765741-158819412:- | 5 | 11.5 |
plasminogen | ENSG00000122194 | PLG | chr6:160702238-160753315:+ | 5 | 8 |
olfactory receptor family 9 subfamily A member 1 pseudogene | ENSG00000237621 | OR9A1P | chr7:141887148-141888092:+ | 5 | 5.5 |
olfactory receptor family 2 subfamily F member 1 (gene/pseudogene) | ENSG00000213215 | OR2F1 | chr7:143959927-143961015:+ | 5 | 5.5 |
LYN proto-oncogene, Src family tyrosine kinase | ENSG00000254087 | LYN | chr8:55879813-56014168:+ | 6 | 9 |
LY6/PLAUR domain containing 2 | ENSG00000197353 | LYPD2 | chr8:142750150-142752534:- | 5 | 5 |
scribble planar cell polarity protein | ENSG00000180900 | SCRIB | chr8:143790920-143815379:- | 6 | 10 |
spleen associated tyrosine kinase | ENSG00000165025 | SYK | chr9:90801787-90898549:+ | 5 | 6 |
olfactory receptor family 1 subfamily B member 1 (gene/pseudogene) | ENSG00000280094 | OR1B1 | chr9:122628579-122629573:- | 5 | 5.5 |
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